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Background And Objectives: Proper symptom management, informal caregiver support, and service innovation are required to reduce dementia care burden. The objective of this study is to investigate the effect of the multicomponent LIVE (Learning, Innovation, Volunteering, Empowerment) intervention on caregiver experience of the self-perceived care situation, coordinator performance, and informal care time.
Research Design And Methods: We conducted a 24-month multicomponent, stepped-wedge randomized control trial including dyads of people ≥65 years with mild-to-moderate dementia with minimum weekly contact with their informal caregivers in Norway. The intervention was implemented by municipal coordinators over a 6-month period. This study investigates the first 6-month period (September 2019-March 2020) of the trial, due to the coronavirus disease 2019 (COVID-19) pandemic. Primary outcomes are changes in provision of informal care time assessed by Resource Utilization in Dementia Care (RUD) and informal caregiver experience assessed by the Clinical Global Impression of Change (CGIC). We use logistic regression and feedback system analysis to assess the reach of the multicomponent intervention.
Results: A total of 280 dyads were included at baseline, mean age of the person with dementia was 81.8 years, and 62.5% were female. After 6 months, the feedback system analysis reveals that the caregivers randomized to the intervention period reported improved caregiver situation (CGIG-T: intervention 0.63 ( 2.4) vs control -0.43 ( 1.7), < .01), even though informal care time for activities of daily living was not reduced ( = .31). Informal caregivers registered a positive change for the Learning, Innovation, and Empowerment components, while no change was found for Volunteer support.
Discussion And Implications: Findings illustrate the usefulness of dementia care coordinators that provide regular follow-up. We also show that complex intervention studies benefit from applying feedback system analysis. Meeting the needs of persons with dementia and their caregivers is a complex process that requires coordinated input from health services and user communities.
Clinical Trial Registration Number: NCT04043364.
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http://dx.doi.org/10.1093/geroni/igae020 | DOI Listing |
Front Health Serv
December 2024
Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Objective: Centering birthing parents is critical for improving reproductive health policies and practices. This study investigates patient perspectives on measuring the quality of perinatal care.
Methods: A cross-sectional qualitative research study was conducted at an academic medical center in the Southeastern United States.
J Ind Ecol
December 2024
Department of Chemistry and Applied Bioscience, Institute for Chemical and Bioengineering ETH Zurich Zurich Switzerland.
This work presents the PULPO (ython-based ser-defined ifecycle roduct ptimization) framework, developed to efficiently integrate life cycle inventory (LCI) models into life cycle product optimization. Life cycle optimization (LCO), which has found interest in both the process systems engineering and life cycle assessment (LCA) communities, leverages LCA data to go beyond simple assessments of a limited number of alternatives and identify the best possible product systems configuration subject to a manifold of choices, constraints, and objectives. However, typically, aggregated inventories are used to build the optimization problems.
View Article and Find Full Text PDFJ Biol Rhythms
December 2024
Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
In both diurnal and nocturnal species, the neurons in the suprachiasmatic nucleus (SCN) generate a daily pattern in which the impulse frequency peaks at midday and is lowest during the night. This pattern, common to both day-active and night-active species, has led to the long-standing notion that their functional difference relies merely on a sign reversal in SCN output. However, recent evidence shows that the response of the SCN to the animal's physical activity is opposite in nocturnal and diurnal animals.
View Article and Find Full Text PDFPlant Cell Environ
December 2024
Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Tokyo, Japan.
Histone modification is a cellular process for transcriptional regulation. In herbivore-damaged plants, activation of genes involved in defence responses is required for antiherbivore properties, but little is known about how the chromatin remodelling system is involved. In Arabidopsis (Arabidopsis thaliana) plants responding to Spodoptera litura larvae, HAC1 and HDA6, a histone acetyltransferase and a histone deacetylase, respectively, were found here to be involved in histone H3 (Lys9; H3K9) acetylation/deacetylation at the promoter region of the plant defensin gene PDF1.
View Article and Find Full Text PDFNew Phytol
December 2024
CAS Kay Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, 110016, China.
Coarse roots represent a globally important belowground carbon pool, but the factors controlling coarse root decomposition rates remain poorly understood relative to other plant biomass components. We compiled the most comprehensive dataset of coarse root decomposition data including 148 observations from 60 woody species, and linked coarse root decomposition rates to plant traits, phylogeny and climate to address questions of the dominant controls on coarse root decomposition. We found that decomposition rates increased with mean annual temperature, root nitrogen and phosphorus concentrations.
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