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Analysis of the Snake Venom Peptidome. | LitMetric

Analysis of the Snake Venom Peptidome.

Methods Mol Biol

Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Published: April 2024

Snake venom peptidomes are known to be a large source of molecules with different pharmacological properties. The complexity and variability of snake venoms, the presence of proteinases, and the lack of complete species-specific genome sequences make snake venom peptidome profiling a challenging task that requires especial technical strategies for sample processing and mass spectrometric analysis. Here, we describe a method for assessing the content of snake venom peptides and highlight the importance of sampling procedures, as they substantially influence the peptidomic complexity of snake venoms.

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Source
http://dx.doi.org/10.1007/978-1-0716-3646-6_17DOI Listing

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