AI Article Synopsis
- Metabolomics is the study of small molecules in biological samples and has recently provided new insights into pulmonary diseases and critical conditions.
- This article introduces key concepts of metabolomics research, including methodologies and statistical analysis techniques.
- It also showcases examples of metabolomics in pulmonary and critical care, highlighting its potential to enhance understanding of diseases and improve personalized patient care in the future.
Article Abstract
In recent years, metabolomics, the systematic study of small-molecule metabolites in biological samples, has yielded fresh insights into the molecular determinants of pulmonary diseases and critical illness. The purpose of this article is to orient the reader to this emerging field by discussing the fundamental tenets underlying metabolomics research, the tools and techniques that serve as foundational methodologies, and the various statistical approaches to analysis of metabolomics datasets. We present several examples of metabolomics applied to pulmonary and critical care medicine to illustrate the potential of this avenue of research to deepen our understanding of pathophysiology. We conclude by reviewing recent advances in the field and future research directions that stand to further the goal of personalizing medicine to improve patient care.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11225873 | PMC |
| http://dx.doi.org/10.1165/rcmb.2024-0080PS | DOI Listing |
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