AI Article Synopsis
- A 28-year-old woman with untreated high blood pressure for 5 years was hospitalized due to breathing issues, coughing up blood, and eye problems.
- Imaging revealed lung plaques and she experienced kidney damage, low platelets, and anemia.
- After 8 weeks of antihypertensive treatment, her kidney function improved, leading to a diagnosis of malignant nephrosclerosis linked to a hypertensive crisis.
Article Abstract
A 28-year-old woman with a 5-year history of untreated hypertension was admitted for respiratory distress, hemoptysis, and retinopathy. Computed tomography showed diffuse plaques in both lung fields. Acute kidney injury, hemolytic anemia, and thrombocytopenia were noted. Kidney biopsy showed thrombosis with fibrinoid necrosis and edematous intimal thickening and luminal narrowing of the small renal artery, indicating thrombotic microangiopathy; the majority of glomeruli were collapsed. After 8 weeks of treatment with antihypertensive drugs, serum creatinine decreased to 1.0 mg/dL, and the patient recovered. In the absence of any other underlying disease, malignant nephrosclerosis associated with a hypertensive emergency was diagnosed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608196 | PMC |
| http://dx.doi.org/10.1007/s13730-024-00863-5 | DOI Listing |
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