This review article examines the synthetic pathways for triazolothiadiazine derivatives, such as triazolo[3,4-]thiadiazines, triazolo[5,1-]thiadiazines, and triazolo[4,3-]thiadiazines, originating from triazole derivatives, thiadiazine derivatives, or thiocarbohydrazide. The triazolothiadiazine derivatives exhibit several biological actions, including antibacterial, anticancer, antiviral, antiproliferative, analgesic, anti-inflammatory, and antioxidant properties. The review article aims to assist researchers in creating new biologically active compounds for designing target-oriented triazolothiadiazine-based medicines to treat multifunctional disorders.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10975507PMC
http://dx.doi.org/10.3390/molecules29061326DOI Listing

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