Transcription Factor MYB as Therapeutic Target: Current Developments.

Int J Mol Sci

Institute for Biochemistry, University of Münster, 48149 Münster, Germany.

Published: March 2024

The MYB protein is a pivotal player in the cellular transcriptional network, influencing major important processes such as cell proliferation, differentiation, and apoptosis. Because of its role in oncogenesis, MYB is now a compelling target for therapeutic interventions in cancer research. This review summarizes its molecular functions and current therapeutic approaches aiming to inhibit its oncogenic activity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10970396PMC
http://dx.doi.org/10.3390/ijms25063231DOI Listing

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