Pregnancy in Glomerular Disease: From Risk Identification to Counseling and Management.

J Clin Med

Unit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, Azienda Ospedaliera Universitaria "G. Martino", University of Messina, 98124 Messina, Italy.

Published: March 2024

: Pregnancy involves complex hemodynamic and immune adaptations to support the developing fetus. The kidney assumes a pivotal role in orchestrating these mechanisms. However, renal disease poses a potential risk for adverse maternal-fetal outcomes. While kidney function, hypertension, and proteinuria are recognized as key influencers of risk, the mere presence of glomerular disease, independent of these factors, may wield significant impact. : A brief review of the existing literature was conducted to synthesize current knowledge regarding the interplay between glomerulonephritis and pregnancy. : The review underscores the centrality of the kidney in the context of pregnancy and highlights the role of glomerular disease, particularly when active. It emphasizes multifaceted risk modulators, including kidney function, hypertension, and proteinuria. : Understanding the dynamics between pregnancy and glomerulonephritis is crucial for optimizing maternal and fetal outcomes. Preconception counseling and collaborative nephro-gynecological management emerge as pivotal components in addressing the unique challenges posed by this medical interplay.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10971190PMC
http://dx.doi.org/10.3390/jcm13061693DOI Listing

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