The Special Issue "Diabetes Mellitus: Current Research and Future Perspectives" is focused on the importance of customized medicine in monogenic diabetes of the young (MODY) and type 2 diabetes (T2D) [...].
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10971381 | PMC |
| http://dx.doi.org/10.3390/jpm14030308 | DOI Listing |
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Platelet-Rich Plasma in the Treatment of Diabetic Foot Ulcers.
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January 2025
At Mayo Clinic, Rochester, Minnesota, United States, Paul T. Gomez, BS, is Summer Research Fellow, Regenerative Sciences Track, Mayo Clinic Graduate School of Biomedical Sciences; Saranya P. Wyles, MD, PhD, is Consultant, Department of Dermatology; and Karen L. Andrews, MD, is Director, Vascular Ulcer and Wound Healing Clinic/Gonda Vascular Center, and Consultant, Department of Physical Medicine and Rehabilitation. At Mayo Clinic, Jacksonville, Florida, Jennifer R. Arthurs is APRN, Center for Regenerative Medicine; and Alison J. Bruce, MB, ChB, is Consultant, Department of Dermatology.
Background: Chronic nonhealing neuropathic foot ulcers affect approximately 15% to 30% of patients with diabetes mellitus and are associated with significant morbidity and mortality. Although current strategies to address these chronic wounds include a multifactorial approach, clinical outcomes remain poor and warrant improvement. Platelet-rich plasma (PRP), derived from autologous or allogeneic blood, is an emerging regenerative product that aims to serve as an adjuvant to standard diabetic foot ulcer (DFU) treatment.
View Article and Find Full Text PDFFactors influencing adherence to dietary recommendations for type 2 diabetes mellitus and their impact on disease control: A cross-sectional study.
J Family Med Prim Care
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Community Medicine Department, Shree M. P. Shah Government Medical College, Jamnagar, Gujarat, India.
Background And Objectives: Diabetes is a chronic metabolic disease, with current estimates by the IDF (International Diabetes Federation) suggesting nationwide prevalence rates of 9.2% among Indians aged 20-79 years. An appropriate dietary pattern is widely accepted as a cornerstone of treatment among diabetes patients.
View Article and Find Full Text PDFImpact of gestational diabetes on depression and breastfeeding self-efficacy in the postpartum period in a selected hospital of Bhubaneswar.
J Family Med Prim Care
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Department of Obstetric and Gynaecology Nursing, Kalinga Institute of Nursing Sciences, KIIT Deemed to be University, Patia, Bhubaneswar, Odisha, India.
Background: Gestational diabetes mellitus (GDM) is the most common medical complication and metabolic disorder of pregnancy. The prevalence of GDM in all pregnancies is approximately 7%. Globally, there are 14% pregnancies with significant variability in prevalence based on diagnostic criteria, sociodemographic characteristics, and geographic region.
View Article and Find Full Text PDFThe Role of Empiric Antifungal Therapy in Patients With Perforated Peptic Ulcer: An Updated Systematic Review and Meta-Analysis.
Am Surg
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Department of Surgery, Division of Acute Care Surgery and Surgical Critical Care, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Fungal growth is common in intraoperative cultures of patients with perforated peptic ulcer (PPU) leading to the common use of empiric antifungal therapy, with current evidence not clearly supporting this practice. The goal of this updated systematic review and meta-analysis was to synthesize the effect of empiric antifungals in patients with PPU. Eligible studies were identified through a comprehensive literature search in the MEDLINE (PubMed) and EMBASE databases, following the PRISMA 2020 statement.
View Article and Find Full Text PDFEvaluation of the implementation in primary care of genetic testing for the screening of MODY2 (iMOgene): protocol for an implementation pilot study.
BMJ Open
January 2025
Research Centre of Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-Saint-Jean (CIUSSS-SLSJ), Saguenay, Quebec, Canada
Introduction: MODY2 (maturity-onset diabetes of the young type 2, MIM125851) is a monogenic diabetes with an autosomal dominant transmission caused by a variant of the gene. MODY2 is often confused with type 1 or type 2 diabetes, but despite a slightly elevated blood glucose level, it does not induce long-term vascular complications, nor does it require pharmacological treatment. Genetic testing for the diagnosis of MODY2 is currently reserved for genetic specialists and some physicians.
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