AI Article Synopsis
- - The manuscript provides a systematic review of malignant Brenner tumors, which are uncommon ovarian tumors comprising less than 1% of all malignant ovarian neoplasms.
- - A total of 48 studies were analyzed, encompassing 115 cases from the English literature, focusing on various patient characteristics and outcomes.
- - Findings indicated that tumor stage, presence of ascites, and abnormal CA-125 levels were linked to recurrence, while lymphadenectomy was associated with improved disease-specific survival.
Article Abstract
Background: Malignant Brenner tumors are rare ovarian tumors, accounting for less than 1% of malignant ovarian neoplasms. The aim of this manuscript is to systematically review the current literature concerning malignant Brenner tumors.
Methods: We searched three medical databases (PubMed, Scopus, and Web of Science) for relevant articles published until 15 September 2023.
Results: After applying inclusion and exclusion criteria, 48 manuscripts describing 115 cases were included in this study from the English literature.
Conclusions: We analyzed the demographic, clinical, pathological, and oncological characteristics of 115 patients with malignant Brenner tumors. The statistical analysis showed that recurrence was marginally statistically significantly related to tumor stage and was more common in patients with ascites and in women with abnormal CA-125 levels; patients that were treated with lymphadenectomy had better disease-specific survival.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968811 | PMC |
| http://dx.doi.org/10.3390/cancers16061106 | DOI Listing |
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