AI Article Synopsis
- The letter discusses how new types of cryptic proteins produced by TDP-43 dysfunction could indicate TDP-43-related issues in neurodegenerative diseases.
- It highlights the significance of these novel proteins as potential biomarkers for diagnosing or understanding these diseases.
- The findings could lead to improved methods for detecting and studying conditions linked to TDP-43 pathology, such as ALS and frontotemporal dementia.
Article Abstract
This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10967196 | PMC |
| http://dx.doi.org/10.1186/s13024-024-00718-8 | DOI Listing |
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