AI Article Synopsis

  • * Data was collected from 329 patients who underwent ABFB at 12 centers between 2016 and 2021, finding no major differences in demographics or complications between the two treatment groups.
  • * Results showed that while primary ABFB had a higher 5-year primary patency rate (88% vs 69% for post-EVT), secondary patency and limb salvage rates were similar for both groups, suggesting both approaches are safely effective.

Article Abstract

Objective: The aim of this multicenter national study was to compare the outcomes of primary open surgery by aorto-bifemoral bypass (ABFB) with those performed after a failed endovascular treatment (EVT) by kissing stent technique for complex aortoiliac occlusive disease (AIOD) lesions (TransAtlantic Inter-Society Consensus [TASC] II C and D).

Methods: All consecutive ABFB cases carried out at 12 vascular surgery centers between 2016 and 2021 were retrospectively collected and analyzed. Data included patients' baseline demographics and clinical characteristics, procedural details, perioperative outcomes, and follow-up results (survival, patency, amputation). The study cohort was divided into two groups based on indications for ABFB: primary treatment vs secondary treatment after EVT failure.

Results: Overall, 329 patients underwent ABFB during the study period (71% males; mean age, 64 years), of which 285 were primary treatment and 44 were after prior EVT. At baseline, no significant differences were found between study groups in demographics and clinical characteristics. TASC C and D lesions were similarly represented in the study groups (TASC C: 22% vs 78%; TASC D: 16% vs 84%). No major differences were found between study groups in terms of procedural details, early mortality, and perioperative complications. At 5 years, primary patency rates were significantly higher for primary ABFB (88%; 95% confidence interval [CI], 93.2%-84%) as compared with ABFB after prior EVT (69%; 95% CI 84.9%-55%; log rank P value < .001); however, the 5-year rates of secondary patency (100% vs 95%; 95% CI, 100%-86%) and limb salvage (97%; 95% CI, 99%-96 vs 97%; 95% CI, 100%-94%) were similar between study groups.

Conclusions: Surgical treatment of TASC C/D AIOD with ABFB seems to be equally safe and effective when performed after prior EVT, although primary ABFB seemed to have higher primary patency rates. Despite the need for more frequent reinterventions, secondary patency and limb salvage rates were similar. However, future large prospective trials are required to confirm these findings.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jvs.2024.03.027DOI Listing

Publication Analysis

Top Keywords

prior evt
12
study groups
12
abfb
8
treatment evt
8
demographics clinical
8
clinical characteristics
8
procedural details
8
primary treatment
8
differences study
8
primary patency
8

Similar Publications

Bridging thrombolysis versus direct endovascular treatment in acute vertebrobasilar artery complex occlusion.

J Neurosurg

January 2025

1Department of Neurology, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui.

Objective: Endovascular treatment (EVT) is an effective treatment for patients with acute vertebrobasilar artery complex occlusion (VBAO). However, the benefit of bridging thrombolysis prior to EVT remains controversial. The purpose of the present study is to explore the best treatment strategy between bridging treatment (BT) and direct EVT in patients with acute VBAO.

View Article and Find Full Text PDF

Effect of prior use of statins on endovascular thrombectomy outcomes in acute ischemic stroke.

Clin Neurol Neurosurg

January 2025

Department of Neurology, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, PA, USA. Electronic address:

Introduction: Acute large vessel occlusions (LVOs) account for up to one-third of acute ischemic strokes (AIS) and are associated with high mortality and severe functional deficits. Animal model research suggests that statins may have a protective effect on vessel wall injury during endovascular thrombectomy (EVT). We conducted a retrospective observational study to assess the impact of statin use on clinical outcomes post-EVT in AIS patients with LVOs.

View Article and Find Full Text PDF

Discrete event simulation model of an acute stroke treatment process at a comprehensive stroke center: Determining the ideal improvement strategies for reducing treatment times.

J Neurol Sci

December 2024

Department of Industrial Engineering, Faculty of Engineering, Dalhousie University, Halifax, Canada; Division of Neurology, Department of Medicine, Dalhousie University, Halifax, Canada; Department of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, Canada.

Background: Fast treatment is crucial for ischemic stroke patients; the probability of good patient outcomes increases with faster treatment. Treatment times can be improved by making changes to the treatment process. However, it is challenging to identify the benefits of changes prior to implementation.

View Article and Find Full Text PDF

Hyperdense Middle Cerebral Artery Sign as a Predictor of First-Pass Recanalization and Favorable Outcomes in Direct Thrombectomy Patients.

Clin Neuroradiol

December 2024

Interventional Neuroradiology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.119 South 4th Ring West Road, 100070, Fengtai District, Beijing, China.

Background: The Hyperdense Middle Cerebral Artery Sign (HMCAS) is an early marker of acute MCA occlusion on non-contrast CT (NCCT), which has been linked with stroke type and thrombus composition.

Aims: To assess the prognostic value of HMCAS in M1 occlusion patients treated with endovascular thrombectomy and explore its predictive value across different patients.

Methods: Patients with M1 occlusion were selected from the ANGEL-ACT registry, which comprised 1793 individuals.

View Article and Find Full Text PDF
Article Synopsis
  • Recent studies indicate that endovascular treatment (EVT) alone is as effective as combining intravenous thrombolysis with EVT (IVT + EVT) for treating acute ischemic stroke due to large-vessel occlusion, although some research suggests specific patient subgroups may benefit more from IVT.
  • This study analyzed data from 238 patients who underwent EVT or IVT + EVT to determine how collateral circulation affects clinical outcomes, using various statistical methods to control for factors like age and stroke severity.
  • Findings revealed that patients with good collateral circulation had significantly better outcomes at 90 days, including lower disability scores, higher success rates of recanalization, and reduced rates of complications such as hemorrhage and mortality.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!