AI Article Synopsis
- Proteomic and metabolomic research helps analyze the molecular profiles of athletes, particularly during aerobic activities like running at high altitudes.
- Changes in specific metabolites, such as 4-hydroxyproline and methionine, were observed during recovery, indicating metabolic shifts.
- Proteomic analysis showed variations in protein expression related to immune function, muscle damage, and athlete performance, suggesting a need for further studies on metabolic models to track training intensity and adaptation.
Article Abstract
Proteomic and metabolomic research enables quantitation of the molecular profile of athletes. Multiomic profiling was conducted using plasma samples collected from 18 male athletes performing aerobic activity (running) at high altitude. Metabolomic profiling detected changes in the levels of 4-hydroxyproline, methionine, oxaloacetate, and tyrosine during the recovery period. Furthermore, proteomic profiling revealed changes in expression of proteins contributing to the function of the immune system, muscle damage, metabolic fitness and performance, as well as hemostasis. Further research should focus on developing metabolic models to monitor training intensity and athlete adaptation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10975304 | PMC |
| http://dx.doi.org/10.3390/sports12030072 | DOI Listing |
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