Challenges in Toxocariasis Diagnosis: From Pericarditis, through Hepatic Tumor, to the Detection of Brain Aneurysms: Case Report.

Pathogens

Department of Infectious Diseases, Liver Diseases and Acquired Immune Deficiences, Wroclaw Medical University, 51-149 Wroclaw, Poland.

Published: March 2024

AI Article Synopsis

  • The condition can lead to visceral and ocular larva migrans, with rare cases involving the central nervous system (neurotoxocariasis), potentially causing serious issues like meningitis or seizures.
  • There is concern about the underdiagnosis of neurotoxocariasis due to its vague symptoms, and while a link to aneurysms hasn't been proven, it's suggested as an area for future research.

Article Abstract

Toxocariasis is the parasitic infection caused by the larvae of roundworms species: from dogs and, less frequently, from cats. The high proportion of asymptomatic cases of toxocariasis and the uncharacteristic clinical manifestations mimicking other medical conditions make diagnosis challenging. The main clinical presentations of toxocariasis are visceral and ocular larva migrans. Migration to the central nervous system (neurotoxocariasis) is rare and can cause meningitis, encephalitis, myelitis, cerebral vasculitis, seizures, headache or asymptomatic CNS infection. Neurotoxocariasis is an uncommon diagnosis and it is probably underdiagnosed due to the nonspecific clinical manifestations, low awareness of physicians as well as the lack of standardized diagnostic exams. To date, no causality has been proven between neurotoxocariasis and aneurysms, but due to the character of immune response elicited by the parasites, it remains an important possibility for further research. We present a case report of a woman infected with highlighting the diagnostic difficulties. We aim to raise the awareness of the clinical symptomatology of neurotoxocariasis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10975517PMC
http://dx.doi.org/10.3390/pathogens13030254DOI Listing

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