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Poincaré plot analysis of ECG uncovers beneficial effects of omaveloxolone in a mouse model of Friedreich's ataxia.
Heart Rhythm
January 2025
Department of Molecular Biosciences, University of California, Davis, CA, USA; Department of Basic Sciences, California Northstate University, Elk Grove, CA. Electronic address:
Background: Friedreich's ataxia (FA) is a rare inherited neuromuscular disorder, where most patients die from lethal cardiomyopathy and arrhythmias. Mechanisms leading to arrhythmic events in FA patients are poorly understood.
Objective: This study aims to examine cardiac electrical signal propagation in mouse model of FA with severe cardiomyopathy and evaluate effects of omaveloxolone (OMAV), the first FDA-approved therapy.
Smart furniture using radar technology for cardiac health monitoring.
Sci Rep
January 2025
Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
The integration of radar technology into smart furniture represents a practical approach to health monitoring, circumventing the concerns regarding user convenience and privacy often encountered by conventional smart home systems. Radar technology's inherent non-contact methodology, privacy-preserving features, adaptability to diverse environmental conditions, and high precision characteristics collectively establish it a compelling alternative for comprehensive health monitoring within domestic environments. In this paper, we introduce a millimeter (mm)-wave radar system positioned strategically behind a seat, featuring an algorithm capable of identifying unique cardiac waveform patterns for healthy subjects.
View Article and Find Full Text PDFDeep learning model for identifying acute heart failure patients using electrocardiography in the emergency room.
Eur Heart J Acute Cardiovasc Care
January 2025
Department of Medical Informatics, Korea University College of Medicine, Seoul, Republic of Korea.
Background: Acute heart failure (AHF) poses significant diagnostic challenges in the emergency room (ER) because of its varied clinical presentation and limitations of traditional diagnostic methods. This study aimed to develop and evaluate a deep-learning model using electrocardiogram (ECG) data to enhance AHF identification in the ER.
Methods: In this retrospective cohort study, we analyzed the ECG data of 19,285 patients who visited ERs of three hospitals between 2016 and 2020; 9,119 with available left ventricular ejection fraction and N-terminal prohormone of brain natriuretic peptide level data and who were diagnosed with AHF were included in the study.
Assessment of conductive textile-based electrocardiogram measurement for the development of a lonely death prevention system.
Biomed Eng Lett
January 2025
Department of Biomedical Engineering, Yonsei University College of Software and Digital Healthcare Convergence, Wonju-si, Gangwon-do 26493 Republic of Korea.
The rise in individuals living alone in ageing societies raises concerns about social isolation and associated health risks, notably lonely deaths among the elderly. Traditional electrocardiogram (ECG) monitoring systems, reliant on intrusive and potentially irritating electrodes, pose practical challenges. This study examines the efficacy of conductive textile electrodes (CTEs) vis-á-vis conventional electrodes (CEs) in ECG monitoring, along with the effect of electrode positioning.
View Article and Find Full Text PDFA new insight into the anatomical ablation approach at R-L ILT for VAs with a left ventricular summit origination: electrophysiological characteristics and catheter ablation.
J Interv Card Electrophysiol
January 2025
Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, No.180, Feng-Lin Road, Shanghai, 200032, P.R. China.
Background: Ventricular arrhythmia (VA) originating from the left ventricular summit (LVS) poses particular challenges, with higher rates of ablation failure.
Objective: To further evaluate the anatomical ablation approach from the subaortic region for LVS VAs and their electrophysiological characteristics.
Method: The study enrolled 27 consecutive patients with sympatomatic VAs originating from LVS and who received an anatomical ablation approach from R-L ILT in our center.
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