AI Article Synopsis
- Extracellular vesicles (EVs), particularly exosomes, have potential in treating diseases by targeting specific cells or tissues, but their effectiveness is hampered by the immune system's ability to clear them during transportation in the body.* -
- Hydrogels serve as a promising delivery method for EVs because of their compatibility with biological systems and their porous design, enhancing the stability and release of EVs.* -
- The article reviews how EVs-loaded hydrogels can be used as a cell-free therapy and addresses the challenges faced and future directions for this innovative treatment strategy.*
Article Abstract
Extracellular vesicles (EVs), especially exosomes, have shown great therapeutic potential in the treatment of diseases, as they can target cells or tissues. However, the therapeutic effect of EVs is limited due to the susceptibility of EVs to immune system clearance during transport in vivo. Hydrogels have become an ideal delivery platform for EVs due to their good biocompatibility and porous structure. This article reviews the preparation and application of EVs-loaded hydrogels as a cell-free therapy strategy in the treatment of diseases. The article also discusses the challenges and future outlook of EVs-loaded hydrogels.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10970166 | PMC |
| http://dx.doi.org/10.3390/gels10030162 | DOI Listing |
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