Computational fluid dynamics is intensively used to deepen our understanding of aneurysm growth and rupture in an attempt to support physicians during therapy planning. Numerous studies assumed fully rigid vessel walls in their simulations, whose sole haemodynamics may fail to provide a satisfactory criterion for rupture risk assessment. Moreover, direct in vivo observations of intracranial aneurysm pulsation were recently reported, encouraging the development of fluid-structure interaction for their modelling and for new assessments. In this work, we describe a new fluid-structure interaction functional setting for the careful evaluation of different aneurysm shapes. The configurations consist of three real aneurysm domes positioned on a toroidal channel. All geometric features, employed meshes, flow quantities, comparisons with the rigid wall model and corresponding plots are provided for the sake of reproducibility. The results emphasise the alteration of flow patterns and haemodynamic descriptors when wall deformations were taken into account compared with a standard rigid wall approach, thereby underlining the impact of fluid-structure interaction modelling.
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http://dx.doi.org/10.3390/bioengineering11030269 | DOI Listing |
Biomech Model Mechanobiol
December 2024
Department of Mechanics and Engineering Science, State Key Laboratory for Turbulence and Complex Systems, Peking University, Beijing, 100871, China.
Central blood pressure (cBP) is considered a superior indicator of cardiovascular fitness than brachial blood pressure (bBP). Even though bBP is easy to measure noninvasively, it is usually higher than cBP due to pulse wave amplification, characterized by the gradual increase in peak systolic pressure during pulse wave propagation. In this study, we aim to develop an individualized transfer function that can accurately estimate cBP from bBP.
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December 2024
Department of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, United States.
The coordinated motion of animal groups through fluids is thought to reduce the cost of locomotion to individuals in the group. However, the connection between the spatial patterns observed in collectively moving animals and the energetic benefits at each position within the group remains unclear. To address this knowledge gap, we study the spontaneous emergence of cohesive formations in groups of fish, modeled as flapping foils, all heading in the same direction.
View Article and Find Full Text PDFSensors (Basel)
November 2024
School of Thermal Engineering, Shandong Jianzhu University, Jinan 250101, China.
This study systematically explores the sources and influencing factors of resistance encountered by magnetic flux leakage (MFL) detectors in natural gas pipelines through a theoretical analysis, experimental investigation, and numerical simulation. The research methodology involves the development of a fluid-structure interaction model using ABAQUS 2023 finite element software, complemented by the design and implementation of a pull-testing platform for MFL detectors. This platform simulates detector operation under various interference conditions and quantifies the resulting frictional resistance.
View Article and Find Full Text PDFEng Comput
June 2024
Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN USA.
Heart valves play a critical role in maintaining proper cardiovascular function in the human heart; however, valve diseases can lead to improper valvular function and reduced cardiovascular performance. Depending on the extent and severity of the valvular disease, replacement operations are often required to ensure that the heart continues to operate properly in the cardiac system. Transcatheter aortic valve replacement (TAVR) procedures have recently emerged as a promising alternative to surgical replacement approaches because the percutaneous methods used in these implant operations are significantly less invasive than open heart surgery.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, 02139-4307, USA.
Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However, their use is currently limited by complex workflows necessitating lengthy expert-driven manual operations.
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