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Insomnia and aggression in stable schizophrenic patients: The mediating role of quality of life. | LitMetric

Insomnia and aggression in stable schizophrenic patients: The mediating role of quality of life.

Schizophr Res

Department of Psychology and Sleep Medicine, the Second Affiliated Hospital of Anhui Medical University, Hefei City, People's Republic of China; School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei City, People's Republic of China. Electronic address:

Published: May 2024

AI Article Synopsis

  • Aggression is a notable concern in schizophrenia patients, potentially linked to insomnia and quality of life, and this study investigates how quality of life affects the relationship between these factors.
  • Data from 781 stable schizophrenia patients demonstrated that around 16% exhibited aggressive behavior, with pathway analysis revealing that quality of life partially mediates the connection between insomnia and aggression.
  • The findings underscore that insomnia notably impacts aggression levels, indicating a need for future focus on improving quality of life as a means to reduce aggression in these patients.

Article Abstract

Unlabelled: Aggression in schizophrenia patients is an issue of concern. Previous studies have shown that aggression in schizophrenia patients may be related to insomnia and quality of life to different extents. This study aimed to explore the potential mediating role of quality of life in the relationship between aggression and insomnia among schizophrenia patients. Demographic factors affecting aggression in schizophrenia patients were also explored.

Patients And Methods: A total of 781 stable patients aged 18-75 who met the ICD10 diagnosis of "schizophrenia" completed the completed questionnaire. Aggression was assessed using the Modified Overt Aggression Scale (MOAS), sleep was assessed using the Insomnia Severity Index Scale (ISI), and quality of life was assessed using the five Likert options. Descriptive statistics and correlation analysis examined the correlation between aggression and other variables. The mediating role of quality of life in the association between insomnia and aggression was examined by pathway analysis.

Results: A total of 781 patients participated in this study, and approximately 16 % of the schizophrenia patients were aggressive. According to the mediation analysis, the direct effect of insomnia on aggression was 0.147, and the mediating effect of quality of life on insomnia and aggression was 0.021. Specifically, for the four dimensions of the MOAS, the direct effects of insomnia on verbal aggression, aggression toward property, and aggression toward oneself were 0.028, 0.032, and 0.023, respectively, with mediating effects of 0.003, 0.007, and 0.006, respectively, and no mediating effect on physical aggression was found.

Conclusion: This study showed that insomnia significantly influenced aggression in schizophrenia patients. Quality of life significantly mediated insomnia and aggression and played a vital role in moderating aggression. Therefore, we suggest that in the future, improving aggression in schizophrenia patients, while paying attention to the importance of sleep, could start with improving quality of life to address this problem from multiple perspectives.

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Source
http://dx.doi.org/10.1016/j.schres.2024.03.024DOI Listing

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