AI Article Synopsis
- Composite lymphoma is a rare type of cancer that includes both diffuse large B-cell lymphoma (DLBCL) and peripheral T-cell lymphoma (PTCL-NOS) occurring in the same organ, with this case involving a 75-year-old man who had intestinal obstruction.
- After surgery to remove part of the small intestine, the patient was diagnosed with composite DLBCL and PTCL-NOS and treated with a rituximab-based chemotherapy that initially led to complete remission.
- Despite initial success, the patient experienced a recurrence of the disease ten months later and, after refusing additional surgery, he survived for 20 months post-diagnosis, prompting a literature review on this lymphoma type's characteristics and treatment options.
Article Abstract
Composite lymphoma is an uncommon type of lymphoid malignancy, and those consisting of concurrent diffuse large B-cell lymphoma (DLBCL) and peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) in the same organ are rare. Here, we report a case of a 75-year-old male patient admitted to our emergency department with intestinal obstruction presenting with abdominal pain and vomiting. He underwent partial resection of the small intestine under general anesthesia, and subsequent histopathology confirmed the mass to be composite DLBCL and PTCL-NOS. The patient received chemotherapy with a rituximab-based regimen and achieved complete remission (CR). However, the recurrent disease presented with obstruction again ten months after treatment. He refused a second surgery, but salvage treatment was not effective. The patient survived for 20 months after diagnosis. In addition, we did a literature review to understand the clinical features, pathology, treatment, and prognosis of this type of composite lymphoma.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10961394 | PMC |
| http://dx.doi.org/10.3389/fonc.2024.1272209 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A multisite validation of brain white matter pathways of resilience to chronic back pain.
Elife
December 2024
Institute of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Chronic back pain (CBP) is a global health concern with significant societal and economic burden. While various predictors of back pain chronicity have been proposed, including demographic and psychosocial factors, neuroimaging studies have pointed to brain characteristics as predictors of CBP. However, large-scale, multisite validation of these predictors is currently lacking.
View Article and Find Full Text PDFNickel oxide (NiO) is known for its remarkable theoretical specific capacity, making it a highly appealing option for electrode materials in electrochemical energy storage applications. Nevertheless, its practical use is limited by poor electrochemical performance and complicated electrode fabrication processes. To address these issues, we propose a new anode design comprising an intermediate NiO nanoarray layer and a carbon coating layer grown directly on a three-dimensional (3D) conductive nickel foam substrate, designated as C@NiO@Ni foam.
View Article and Find Full Text PDFDiffuse large B-cell lymphoma mimicking the cervical epidural hematoma in a patient who underwent spinal manipulation therapy: a case report and literature review.
J Surg Case Rep
January 2025
Neurosurgery Department, Medical University of Gdansk, Gdansk 80-952, Poland.
The diffuse large B-cell lymphoma (DLBCL) mimicking an epidural hematoma in the cervical spine is an extremely unique case. We present a case of a 42-year-old man, who presented to the emergency department with symptoms of tetraparesis after a session of spinal manipulation therapy. magnetic resonance imaging visualized a lesion located at C3-C7 causing spinal cord compression with surrounding soft tissue edema suggesting epidural hematoma.
View Article and Find Full Text PDFEvaporative Morphology Tuning of Conducting Polymer Films Under Controlled Vacuum Conditions.
Adv Sci (Weinh)
December 2024
Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-gu, Pohang, 37673, Republic of Korea.
The evaporation of drops on solid surfaces is a ubiquitous natural phenomenon, and their dynamics play a pivotal role in many biological, environmental, and industrial processes. However, the complexity of the underlying mechanisms has largely confined previous studies to liquid drop evaporation under atmospheric conditions. In this study, the first comprehensive investigation of the evaporation dynamics of conducting polymer-containing drops under controlled vacuum environments is presented.
View Article and Find Full Text PDFBaseline Tumor Burden Assessed With AI-Guided PET/CT Total Metabolic Tumor Volume (TMTV) and LDH Levels Predict Efficacy of CAR-T in Aggressive B-Cell Lymphoma.
Hematol Oncol
January 2025
Dipartimento di Scienze di Laboratorio Ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Disease burden is a critical determinant of outcomes in CAR-T therapy for B-cell lymphomas, and one of the most widely used techniques for its assessment is Total Metabolic Tumor Volume (TMTV) measured via [F]FDG PET/CT. Biological parameters may further refine the risk profile. We analyzed baseline [F]FDG PET/CT scans from 40 patients treated with CAR-T, using an AI-based automated segmentation algorithm to determine TMTV.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!