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Background: Belzutifan, a first-in-class HIF-2α inhibitor, has shown antitumour activity as monotherapy and in combination with cabozantinib in patients with previously treated advanced kidney cancer. The phase 2 LITESPARK-003 study was designed to determine the antitumour activity and safety of belzutifan in combination with cabozantinib in patients with advanced clear-cell renal cell carcinoma that was previously untreated (cohort 1) or previously treated with immunotherapy (cohort 2). Here, we report results from cohort 1 of this clinical trial.
View Article and Find Full Text PDFRacial and Ethnic Diversity in American Plastic Surgery Residency.
J Surg Educ
December 2024
Department of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address:
Introduction: Significant efforts during the past decades have led to growing racial diversity in the field, resulting in more underrepresented minorities (URM) in training. To highlight areas for improving URM inclusion and training, we sought to pinpoint educational and achievement gaps among URMs in contrast to White and Asian trainees.
Methods: In this cross-sectional study, publicly accessible records were assessed for data on trainees' education, research, location, and race, comparing URMs (Black, Hispanic, Hawaiian, Native American) to White and Asian trainees.
Preferred Educational Programming Among Graduate Students and Post-doctoral Fellows at Pharmacy Schools: a Pilot Survey.
Am J Pharm Educ
December 2024
University of Mississippi School of Pharmacy, Oxford, MS. Electronic address:
Objective: To inform program development, the AACP Graduate Education Special Interest Group Colleagues in Training Committee (CITC) investigated professional development needs of graduate students and post-doctoral fellows at schools/colleges of pharmacy.
Methods: A cross-sectional pilot survey examined preferred programming topics, mentoring needs, and career goals. A survey invitation was posted on AACP Connect and emailed to Graduate Program Officers and Assistant/Associate Deans for Research at US pharmacy schools/colleges for distribution to trainees.
Role out of Network of Black Male Nursing Leaders Mentorship Program.
Nurs Outlook
December 2024
East Carolina University College of Nursing, Greenville, NC.
Despite nursing being the largest segment in all of the healthcare workforce, with over five million practicing registered nurses in the United States, Black males remain significantly underrepresented, comprising merely about 0.67% to 1% of the nursing workforce. This underrepresentation extends into leadership positions, where the number of Black male leaders in nursing is described as unquantifiable.
View Article and Find Full Text PDFDeconstructing imposter syndrome among BIPOC genetic counseling students: Insights from a longitudinal qualitative study.
J Genet Couns
December 2024
Department of Obstetrics and Gynecology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
"Imposter syndrome" is a term used to describe feelings of pervasive self-doubt despite evident success. It is the lay version of "imposter phenomenon," a concept that was proposed as an explanation for why highly accomplished (mostly white and middle- to upper-class) women persisted in believing that their success was due to luck or a mistake despite evidence to the contrary. However, the experience of imposter syndrome in genetic counseling, particularly among Black, Indigenous, and People of Color (BIPOC) individuals, remains underexplored.
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