The electroencephalogram-based (EEG) brain-computer interface (BCI) has garnered significant attention in recent research. However, the practicality of EEG remains constrained by the lack of efficient EEG decoding technology. The challenge lies in effectively translating intricate EEG into meaningful, generalizable information. EEG signal decoding primarily relies on either time domain or frequency domain information. There lacks a method capable of simultaneously and effectively extracting both time and frequency domain features, as well as efficiently fuse these features. Addressing these limitations, a two-branch Manifold Domain enhanced transformer algorithm is designed to holistically capture EEG's spatio-temporal information. Our method projects the time-domain information of EEG signals into the Riemannian spaces to fully decode the time dependence of EEG signals. Using wavelet transform, the time domain information is converted into frequency domain information, and the spatial information contained in the frequency domain information of EEG signal is mined through the spectrogram. The effectiveness of the proposed TBEEG algorithm is validated on BCIC-IV-2a dataset and MAMEM-SSVEP-II datasets.
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http://dx.doi.org/10.1109/TNSRE.2024.3380595 | DOI Listing |
J Med Internet Res
January 2025
School of Computer Science, University of Technology Sydney, Sydney, Australia.
The integration of artificial intelligence (AI) into health communication systems has introduced a transformative approach to public health management, particularly during public health emergencies, capable of reaching billions through familiar digital channels. This paper explores the utility and implications of generalist conversational artificial intelligence (CAI) advanced AI systems trained on extensive datasets to handle a wide range of conversational tasks across various domains with human-like responsiveness. The specific focus is on the application of generalist CAI within messaging services, emphasizing its potential to enhance public health communication.
View Article and Find Full Text PDFJMIR Med Inform
January 2025
School of Software, Taiyuan University of Technology, Jingzhong, China.
Background: The prompt and accurate identification of mild cognitive impairment (MCI) is crucial for preventing its progression into more severe neurodegenerative diseases. However, current diagnostic solutions, such as biomarkers and cognitive screening tests, prove costly, time-consuming, and invasive, hindering patient compliance and the accessibility of these tests. Therefore, exploring a more cost-effective, efficient, and noninvasive method to aid clinicians in detecting MCI is necessary.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2025
Department of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan.
Background: The association of maternal hyperglycemia with childhood developmental delay has been examined; however, only 2 studies used maternal blood glucose level as a continuous variable as an exposure. A present study aimed to investigate the influence of maternal fasting plasma glucose (mFPG) level in early gestation on developmental delay in children.
Methods: This cohort study included 1541 mother-child pairs who participated in the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.
Discov Ment Health
January 2025
School of Allied Health Sciences, VIMS Hospital Campus, Vinayaka Mission's Research Foundation - Deemed to be University, Salem, Tamil Nadu, India.
Loneliness and Social Isolation (SI) has evolved into an epidemic and WHO has alarmed many developed and developing countries that their citizens are going through the epidemic of loneliness and SI. It affects the Mental Health status of a person & leads to morbidities and premature death. Loneliness and SI are overlooked subjects resulting in poor research turnover.
View Article and Find Full Text PDFRNA Biol
December 2025
Department of Cell and Molecular Biology, Biomedical Centre, Uppsala University, Uppsala, Sweden.
We show that a small biotin-binding RNA aptamer that folds into a pseudoknot structure acts as a substrate for bacterial RNase P RNA (RPR) with and without the RNase P C5 protein. Cleavage in the single-stranded region in loop 1 was shown to depend on the presence of a RCCA-motif at the 3' end of the substrate. The nucleobase and the 2'hydroxyl at the position immediately 5' of the cleavage site contribute to both cleavage efficiency and site selection, where C at this position induces significant cleavage at an alternative site, one base upstream of the main cleavage site.
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