Background: The introduction into the clinical practice of the navigator nurse (NaNu) to address the task of counseling and short term follow-up help the effective implementation of the fast track protocol. The aim of the present study was to investigate the impact of the standardization of the NaNu's role in patients undergoing liver surgery.
Methods: Patients undergoing elective liver surgery for all diagnosis and approach, from 2015, received counseling and postoperative follow-up by NaNu and constituted the study group (n = 890). This group was compared with the control group (n = 712) including patients treated in the era before the implementation of the NaNu role (2011-2014). Outcome was evaluated in terms of discrepancy between functional recovery and discharge, number of ER accesses, number of readmissions.
Results: Preoperative characteristics of patients and disease, as well as type of resection and postoperative outcomes were similar between the two groups. The proportion of laparoscopic cases was higher in the study group (51.2% vs. 32% in the control). Time for discharge, interval between functional recovery and discharge, number of ER accesses and number of readmissions were reduced in the study group. Benign diagnosis, absence of complications, laparoscopic approach and presence of NaNu were independent predictors of shorter length of stay. The positive effect of NaNu's activation was recorded in patients with complications and undergoing open surgery.
Conclusion: The implementation of NaNu's role has allowed to us optimize the level of healthcare service offered to patients. The wider benefit was offered in the setting of complex patients.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1002/wjs.12026 | DOI Listing |
Sci Rep
January 2025
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Theodor-Stern-Kai 7, 60596, Frankfurt am Main, Germany.
Community-acquired pneumonia (CAP) has a significant impact on public health, especially in light of the recent SARS-CoV-2 pandemic. To enhance disease characterization and improve understanding of the underlying mechanisms, a comprehensive analysis of the plasma lipidome, metabolome and proteome was conducted in patients with viral and bacterial CAP infections, including those induced by SARS-CoV-2. Lipidomic, metabolomic and proteomic profiling were conducted on plasma samples of 69 patients suffering either from viral or bacterial CAP.
View Article and Find Full Text PDFBMJ Open
October 2024
Consellería de Sanidade e o Servizo Galego de Saúde, Santiago de Compostela, Spain.
Introduction: Linezolid is a broadly used antibiotic to treat complicated infections caused by gram-positive bacteria. Therapeutic drug monitoring of linezolid concentrations is recommended to maximise its efficacy and safety, mainly haematological toxicity. Different pharmacokinetic/pharmacodynamic targets have been proposed to improve linezolid exposure: the ratio of the area under the concentration-time curve during a 24-hour period to minimum inhibitory concentration (MIC) between 80 and 120; percentage of time that the drug concentration remains above the MIC during a dosing interval greater than 85% and the trough concentration between 2 and 7 mg/L.
View Article and Find Full Text PDFOur study investigates the post-mortem findings of the diaphragm's muscular structural changes in mechanically ventilated COVID-19 patients. Diaphragm samples of the right side from 42 COVID-19 critically ill patients were analyzed and correlated with the type and length of mechanical ventilation (MV), ventilatory parameters, prone positioning, and use of sedative drugs. The mean number of fibers was 550±626.
View Article and Find Full Text PDFHaematologica
August 2024
Miloš Mladenović, ;Charlotte Flasshove, Bojana Mišković, ;José-María Ribera-Santasusana, Martin Hoenigl, Juergen Prattes, Malgorzata Mikulska, Annarosa Cuccaro, Emel Bekirova, Josip Batinić, ;Nick De Jonge, Tatjana Adžić-Vukičević, ;Ľuboš Drgoňa, Hans Martin Orth, Florian Reizine, Monica Piedimonte, Jörg Schubert, Andrés Soto-Silva, Jorge Loureiro-Amigo, Laura Serrano, Lisset Lorenzo De La Peña, Anna Guidetti, Irati Ormazabal-Vélez, Sandra Malak, Maria Calbacho, Noemí Fernández, Rafael F. Duarte, Elizabeth De Kort, Guldane Cengiz Seval, Luisa Verga, Rui Bergantim, María-Josefa Jiménez-Lorenzo, Johan Maertens, Nina Khanna, Matthias Egger, Omar-Francisco Coronel-Ayala, Przemyslaw Zdziarski, Alessandro Busca, Elena Busch, Christian Bjørn Poulsen, François Danion, Tania Cushion, Sergio Pinzón, Yung Gonzaga, Austin Kulasekararaj, Hossein Zarrinfar, Baerbel Hoell-Neugebauer, Chi Shan Kho, Rémy Duléry, Martin Kolditz, Monica Fung, Alina Daniela Tanase.
Ann Intensive Care
March 2024
Department of Emergency and Critical Care Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan.
Background: In some cases of patients with out-of-hospital cardiac arrest (OHCA) who underwent extracorporeal cardiopulmonary resuscitation (ECPR), negative pupillary light reflex (PLR) and mydriasis upon hospital arrival serve as common early indicator of poor prognosis. However, in certain patients with poor prognoses inferred by pupil findings upon hospital arrival, pupillary findings improve before and after the establishment of ECPR. The association between these changes in pupillary findings and prognosis remains unclear.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!