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Role of 3D electro-anatomical mapping on procedural characteristics and outcomes in pulsed-field ablation for atrial fibrillation. | LitMetric

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10984560PMC
http://dx.doi.org/10.1093/europace/euae075DOI Listing

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Article Synopsis
  • The exact causes of common atrial flutter are not fully understood, particularly regarding arrhythmia triggers and the impact of slow-conducting heart tissue.
  • A detailed electrophysiological study was conducted on a patient to investigate how this arrhythmia starts and is maintained, utilizing techniques like electro-anatomical mapping.
  • The study found that common atrial flutter begins with a unidirectional conduction block at the septal cavo-tricuspid isthmus, resulting in a counter-clockwise activation pattern and stabilization near specific heart regions, without any slowing of conduction.
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This review provides insights into mapping and ablation strategies for VT, offering a comprehensive overview of contemporary approaches and future perspectives in the field. The strengths and limitations of classical mapping strategies, namely activation mapping, pace mapping, entrainment mapping, and substrate mapping, are deeply discussed. The increasing pivotal relevance of CMR and MDCT in substrate definition is highlighted, particularly in defining the border zone, tissue channels, and fat.

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pyCEPS: A cross-platform electroanatomic mapping data to computational model conversion platform for the calibration of digital twin models of cardiac electrophysiology.

Comput Methods Programs Biomed

September 2024

Gottfried Schatz Research Center, Division of Medical Physics and Biophysics, Medical University of Graz, Graz, Austria; NumeriCor GmbH, Graz, Austria; BioTechMed-Graz, Graz, Austria. Electronic address:

Background And Objective: Data from electro-anatomical mapping (EAM) systems are playing an increasingly important role in computational modeling studies for the patient-specific calibration of digital twin models. However, data exported from commercial EAM systems are challenging to access and parse. Converting to data formats that are easily amenable to be viewed and analyzed with commonly used cardiac simulation software tools such as openCARP remains challenging.

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: Cardiac magnetic resonance (CMR) imaging has become an essential instrument in the study of cardiomyopathies; it has recently been integrated into the diagnostic workflow for cardiac amyloidosis (CA) with remarkable results. An additional emerging role is the stratification of the arrhythmogenic risk by scar analysis and the possibility of merging these data with electro-anatomical maps. This is made possible by using a software (ADAS 3D, Galgo Medical, Barcelona, Spain) able to provide 3D heart models by detecting fibrosis along the whole thickness of the myocardial walls.

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