AI Article Synopsis

  • A rod-shaped Gram-negative bacterium from the genus has become a significant pathogen for silkworms, showing multi-drug resistance due to excessive antimicrobial use in sericulture.
  • These multi-drug resistant strains can pose health risks to humans through direct contact or contaminated silkworm feces.
  • Researchers sequenced the genome of a strain isolated from infected silkworms, revealing important genetic information that could help understand antimicrobial resistance and the bacterium's virulence.

Article Abstract

Species belonging to the genus is a rod shaped Gram-negative bacteria emerged as an important silkworm pathogen with broad-level multi-drug resistance. The extensive usage of antimicrobials in sericulture farming is gradually leading to the emergence of multi-drug resistance (MDR) strains, posing a significant threat to the well-being of both L. and serifarmers. spp. with MDR level may gets transmitted from the infected silkworm to human handlers either via direct contact or through contaminated feces. To understand the emerging concern of antimicrobial resistance (AMR) in spp. provides insights into their genomic information. Here, we present the draft genome sequence data of sp. strain RAC1 isolated from a flacherie infected Nistari race of L. from the silkworm rearing house of Raiganj University, India and sequenced using the Illumina NovaSeq 6000 platform. The estimated genome size of the strain was 4494347 bp with a G + C content of 63.5%. The assembly of the genome generated 38 contigs with an N50 of 200 kb. Our data might help to reveal the genetic diversity, underlying mechanisms of AMR and virulence potential of spp. This draft-genome shotgun project has been deposited under the NCBI GenBank accession number NZ_JAUTXS000000000.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10957439PMC
http://dx.doi.org/10.1016/j.dib.2024.110293DOI Listing

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