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| http://dx.doi.org/10.1002/hsr2.2007 | DOI Listing |
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A culture-free biphasic approach for sensitive and rapid detection of pathogens in dried whole-blood matrix.
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Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL-61801, USA.
Blood stream infections (BSIs) cause high mortality, and their rapid detection remains a significant diagnostic challenge. Timely and informed administration of antibiotics can significantly improve patient outcomes. However, blood culture, which takes up to 5 d for a negative result, followed by PCR remains the gold standard in diagnosing BSI.
View Article and Find Full Text PDFCulture-free biphasic approach for sensitive detection of Escherichia coli O157:H7 from beef samples.
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Foodborne illnesses are a major threat to public health also leading to significant mortality and financial and reputational damage to industry. It is very important to detect pathogen presence in food products early, rapidly, and accurately to avoid potential outbreaks and economic loss. However, "gold standard" culture methods, including enrichment of pathogens, can take up to several days.
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