AI Article Synopsis

  • * Despite their benefits, these drugs can cause a range of skin-related side effects, including serious conditions like bullous pemphigoid and severe allergic reactions.
  • * The review highlights the importance of awareness among healthcare providers about these dermatological issues, their potential causes, risk factors, and emphasizes the need for more research to improve patient safety.

Article Abstract

Dipeptidyl peptidase-4 (DPP-4) inhibitors are a class of drugs that enhance the incretin-insulin pathway and offer effective glycemic control in type 2 diabetes mellitus. However, these drugs may be associated with various dermatological side effects, ranging from mild to severe. This review article summarizes the current literature on the dermatological side effects of DPP-4 inhibitors, including bullous pemphigoid, severe cutaneous adverse drug reactions, fixed drug eruptions, and other mucocutaneous reactions. The review also discusses the possible mechanisms, risk factors, diagnosis, and management of these side effects. This review aims to increase the awareness and vigilance of healthcare providers in recognizing and managing the dermatological side effects of DPP-4 inhibitors and to emphasize the need for further research and surveillance to optimize diabetes care and patient safety.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10962164PMC
http://dx.doi.org/10.1186/s40842-024-00165-wDOI Listing

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