A 75-year-old woman was referred to our department in October 2022 with ataxia and involuntary movements of the right upper and lower limbs. She had experienced a left pontine hemorrhage in March 2021, which was managed conservatively. However, she had residual right-sided hemiplegia. In addition, she had cerebellar ataxia and a 2 Hz resting tremor of the right upper and lower limbs, which was enhanced while maintaining posture and contemplation. Based on her history, and the findings of MRI and nuclear medicine imaging, we diagnosed the patient with Holmes tremor due to pontine hemorrhage. Holmes tremor is a rare movement disorder secondary to brainstem and thalamic lesions, characterized by a unilateral low-frequency tremor. In this case, I-IMP SPECT and MRI shows damage to the cerebellothalamic tract and dentaro-rubro-olivary pathway.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5692/clinicalneurol.cn-001913 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ultrasonography for Assessment and Intervention With Botulinum Toxin Injection for Tremors.
Ann Rehabil Med
December 2024
Department of Rehabilitation Medicine, National Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea.
Objective: Tremors are caused by contractions of reciprocally innervated muscles. The role of ultrasound in diagnosing tremors has not yet been investigated, although it appears to be promising because it can visualize muscle movements. In the present study, we report four cases of tremor (Holmes' tremor, extremity tremor associated with palatal myoclonus, dystonic tremor, and tremor associated with dystonia), which were evaluated using ultrasound and treated with botulinum toxin injections.
View Article and Find Full Text PDFTremors in cats with hepatic encephalopathy-congenital portosystemic shunts or postattenuation neurological syndrome.
Vet Rec
November 2024
Department of Clinical Science and Services, Royal Veterinary College, Hatfield, UK.
Background: Tremors have been reported as a neurological sign in cats with hepatic encephalopathy due to congenital portosystemic shunts (HE-CPSS) or postattenuation neurological syndrome (PANS).
Methods: The clinical records of cats diagnosed with HE-CPSS and manifesting tremors between 2003 and 2023 were retrospectively reviewed to characterise the clinical features of the tremors.
Results: Nineteen cats with HE-CPSS were included, of which 17 manifested tremors at admission and two had PANS.
Stereotactic robot-assisted MRI-guided laser interstitial thermal therapy thalamotomy for medically intractable Holmes tremor: a pilot study and literature review.
Neurosurg Focus
November 2024
2Expert Center for Parkinson's Disease, Amiens Picardie University Hospital, Amiens.
Article Synopsis
- Holmes tremor (HT) is a disorder that causes different types of tremors and can severely affect a patient's daily life; traditional medications often fail to provide consistent relief.
- This study examines the effectiveness of a new surgical technique, called MRI-guided laser interstitial thermal therapy (MRIgLITT), focusing on its impact on tremor severity, quality of life (QOL), and adverse effects in patients with persistent HT.
- Results showed notable improvements in tremor severity and QOL, with patients experiencing a 41% reduction in tremors at 3 months and a 29% reduction at 12 months post-surgery, indicating the potential benefits of this treatment approach.
Oral and gut microbiome profiles in people with early idiopathic Parkinson's disease.
Commun Med (Lond)
October 2024
23andMe, Inc., Sunnyvale, CA, USA.
Article Synopsis
- * A study of 445 PD patients revealed a higher diversity of microbes compared to 221 controls, with specific bacterial overabundances and depletions identified as key signatures of PD.
- * Findings indicate that certain oral microbiome characteristics could act as potential biomarkers for early PD detection, particularly in relation to non-motor symptoms linked to the peripheral nervous system.
Movement Disorders in Brain Sagging Syndrome Due To Spontaneous Intracranial Hypotension: A Review.
Tremor Other Hyperkinet Mov (N Y)
September 2024
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, US.
Background: Spontaneous intracranial hypotension (SIH), a treatable condition that stems from spinal leakage of cerebrospinal fluid, usually presents with orthostatic headache, nausea, vomiting, dizziness, and tinnitus. A subset of patients, especially those with sagging of brain structures ("brain sagging syndrome"), develop several movement abnormalities. As SIH is treatable with epidural blood patch (EBP), movement disorders neurologists should be familiar with this syndrome.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!