The temporal bisection procedure has been used to assess theories of time perception. A problem with the procedure for measuring the perceived midpoint of two durations is that the spacing of probe durations affects the length of the bisection point. Linear spacing results in longer bisection points closer to the arithmetic mean of the durations than logarithmic spacing. In three experiments, the influence of probe duration distribution was avoided by presenting a single probe duration of either the arithmetic or geometric mean of the trained durations. It was found that the number of participants that categorised the arithmetic mean as long was significantly larger than those that categorised it as short. The number of participants that categorised the geometric mean as either short or long did not significantly differ. This was true for trained durations of 0.4 s vs. 1.6 s (Experiments 1-3), 0.2 s vs. 3.2 s (Experiment 2) and 0.4 s vs. 6.4 s (Experiment 3). In Experiment 4, the probe trial distribution effect was replicated with logarithmic and linearly distributed probe durations, demonstrating that bisection occurs close to the arithmetic mean with linearly spaced probe durations. The results provide evidence against bisection at the arithmetic mean when probe spacing bias is avoided and, instead, the results are consistent with logarithmic encoding of time, or a comparison rule based on relative rather than absolute differences.
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http://dx.doi.org/10.1016/j.cognition.2024.105770 | DOI Listing |
Alzheimers Dement
December 2024
Cornell University, Ithaca, NY, USA.
Background: Spatial disorientation is an early symptom of Alzheimer's disease (AD). The hippocampus creates a cognitive map, wherein cells form firing fields in specific locations within an environment, termed place cells. Critically, place cells remain stable across visits to an environment, but change their firing rate or field location in a different environment.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Cornell University, Ithaca, NY, USA.
Background: Alzheimer's disease (AD) manifests with early spatial memory impairment and is linked to the degeneration of hippocampal circuits. Hippocampal sharp wave ripples (SWRs) are high-frequency population-burst events that coordinate the reactivation of neural assemblies (groups of neurons that become correlated in their firing patterns during learning) in post-learning sleep, which is the neural basis of memory consolidation. SWRs are reduced in the APP/PS1 mouse model of AD-like pathology.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Psychophysiology Laboratory, Indian Institute of Technology, Bombay, Mumbai, Maharashtra, India.
Background: Lexical access refers to the generation or retrieval of conceptual representation. Representation of concepts or semantic knowledge involves the organization of concepts in an associative manner building up the mental lexicon. Several studies have pointed out an early presence of lexical access failure in Alzheimer's Disease(AD).
View Article and Find Full Text PDFFront Aging Neurosci
December 2024
Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ, United States.
Background: The 3xTg-AD transgenic mouse model of Alzheimer's disease (AD) is an important tool to investigate the relationship between development of pathological amyloid-β (Aβ) and tau, neuroinflammation, and cognitive impairments. Traditional behavioral tasks assessing aspects of learning and memory, such as mazes requiring spatial navigation, unfortunately suffer from several shortcomings, including the stress of human handling and not probing species-typical behavior. The automated IntelliCage system was developed to circumvent such issues by testing mice in a social environment while measuring multiple aspects of cognition.
View Article and Find Full Text PDFGround Water Monit Remediat
June 2024
RTI International.
Subslab soil gas (SSSG) samples were collected as part of an investigation to evaluate vapor intrusion (VI) into a building. The June 2015 Office of Solid Waste and Emergency Response (OSWER) VI Guide (U.S.
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