In this article, we introduced a novel salen-type ligand precursor and applied it in the Pd-catalyzed Mizoroki-Heck and Cu-catalyzed -arylation cross-coupling reactions. For the preparation of this structure, ()-phenyl alanine was employed as a starting material. These ligand precursor and related catalytic system can be readily synthesised. Various aryl halides (-I, -Br) and alkenes were applied successfully in this protocol to give the corresponding Mizoroki-Heck cross-coupling and -arylated products in high to excellent yields.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2024.2326853 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Rapid and Efficient Dual Detection Of Zn Ions and Oxytetracycline Hydrochloride Using a Responsive Fluorescent "On-Off" Sensor Based on Simple Salen-Type Schiff Base Ligand.
Chem Asian J
December 2024
Department of Technology of Organic Chemistry and Polymer, Institute of Chemical Technology, Vietnam Academy of Science and Technology, No. 1 A, TL29 Str., Thanh Loc Ward, Dist. 12, Ho Chi Minh City, 70000, Vietnam.
This research has progressed to an effective detection chemosensor of zinc, aluminum ions and oxytetracycline hydrochloride antibiotic based on the fluorescence technique. A straightforward method utilizing microwave irradiation was employed to synthesize the salen-type Schiff base ligand N,N'-bis(salicylaldehyde)4,5-dichloro-1,2-phenylenediamine (HI), providing a good 70 % yield. In ethanol, the HI sensor demonstrated remarkable rapidity, selectivity, and sensitivity in detecting zinc ions.
View Article and Find Full Text PDFHarmonizing Energies: The Interplay Between a Nonplanar SalEn-Type Molecule and a TEMPO Moiety in a New Hybrid Energy-Storing Redox-Conducting Polymer.
Macromol Rapid Commun
July 2024
Saint Petersburg State University 7/9 Universitetskaya nab., St. Petersburg, 199034, Russia.
Redox-conducting polymers based on SalEn-type complexes have attracted considerable attention due to their potential applications in electrochemical devices. However, their charge transfer mechanisms, physical and electrochemical properties remain unclear, hindering their rational design and optimization. This study aims to establish the influence of monomer geometry on the polymer's properties by investigating the properties of novel nonplanar SalEn-type complexes, poly[N,N'-bis(salicylidene)propylene-2-(hydroxy)diaminonickel(II)], and its analog with 2,2,6,6-tetramethylpiperidinyl-N-oxyl (TEMPO)-substituted bridge (MTS).
View Article and Find Full Text PDFDevelopment and synthesis of a novel salen-type ligand based on phenylalanine for Mizoroki-Heck, and -arylation cross-coupling reactions.
Nat Prod Res
March 2024
Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Sultanate of Oman.
In this article, we introduced a novel salen-type ligand precursor and applied it in the Pd-catalyzed Mizoroki-Heck and Cu-catalyzed -arylation cross-coupling reactions. For the preparation of this structure, ()-phenyl alanine was employed as a starting material. These ligand precursor and related catalytic system can be readily synthesised.
View Article and Find Full Text PDFThe prediction of single-molecule magnet properties via deep learning.
IUCrJ
March 2024
Department of Chemistry, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 1628601, Japan.
This paper uses deep learning to present a proof-of-concept for data-driven chemistry in single-molecule magnets (SMMs). Previous discussions within SMM research have proposed links between molecular structures (crystal structures) and single-molecule magnetic properties; however, these have only interpreted the results. Therefore, this study introduces a data-driven approach to predict the properties of SMM structures using deep learning.
View Article and Find Full Text PDFComputational Evaluation of the Potential Pharmacological Activity of Salen-Type Ligands in Alzheimer's Disease.
J Alzheimers Dis
May 2024
Departamento de Química, Universidad Nacionalde Colombia -Sede Bogotá, Bogotá, Colombia.
Background: Alzheimer's disease (AD) is the most common form of dementia representing from 60% to 70% of the cases globally. It is a multifactorial disease that, among its many pathological characteristics, has been found to provoke the metal ion dysregulation in the brain, along with an increase in the oxidative stress. There is proof that metallic complexes formed by the amyloid-β peptide (Aβ) and extraneuronal copper can catalyze the production of reactive oxygen species, leading to an increase in oxidative stress, promoting neuronal death.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!