Iron-mediated induction of bone morphogenetic protein (BMP)6 expression by liver endothelial cells is essential for iron homeostasis regulation. We used multiple dietary and genetic mouse cohorts to demonstrate a minor functional role for the metal-ion transporter ZIP8 in regulating BMP6 expression under high-iron conditions.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443574 | PMC |
| http://dx.doi.org/10.1182/blood.2023023385 | DOI Listing |
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