Spermacosides a and B, two new triterpenoid saponins from burm.f.

Two new triterpenoid saponins, named spermacosides A-B (-), together with two known oleanane-type triterpenoid saponins, 3--D-xylopyranosyl-(1→3)-D-glucopyranosylbayogenin ( and 3---D-glucopyranosylbayogenin (), were isolated from the ethyl acetate extract of Burm.f. in a phytochemical investigation. Their chemical structures were elucidated by spectroscopic data analysis (1D and 2D NMR, and HR-ESI-MS), as well as comparison with reported data. All these compounds were evaluated for inhibiting nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells. Among them, showed a slight effect with an IC value of 108.65 ± 7.91 µM, and compounds were inactive.