A surgical technique has been developed using a robot-assisted system to create the surgical anatomical structure of the uterine artery caudal space (UACS), a landmark for performing extrafascial hysterectomy, enabling a safe and easy parametrial resection to prevent ureteral injury and cervical sidewall bleeding at hysterectomy. UACS is created to preserve the ureterohypogastric nerve fascia (UHNF), which envelopes the ureter and the hypogastric nerve, and the vesicohypogastric fascia (VF), which wraps the uterine artery and veins. The boundaries of UACS are UHNF laterally, the uterine cervix medially, and VF cranially. VF is penetrated between UACS and the medial pararectal space under the uterine vessels and transected. We present a case of early-stage uterine cancer and describe the new surgical technique in detail, using UACS as a surgical landmark. This surgical technique could be applied not only to early-stage uterine cancer but also to benign uterine tumors using a robot-assisted surgical system.
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http://dx.doi.org/10.7759/cureus.54512 | DOI Listing |
Sci Rep
December 2024
Laboratory of Molecular and Cellular Immunology, Institute of Molecular Biology NAS RA, 7 Hasratyan Str., Yerevan, 0014, Armenia.
Antiphospholipid syndrome (APS) is associated with recurrent pregnancy morbidity, yet the underlying mechanisms remain elusive. We performed multifaceted characterization of the biological and transcriptomic signatures of mouse placenta and uterine natural killer (uNK) cells in APS. Histological analysis of APS placentas unveiled placental abnormalities, including disturbed angiogenesis, occasional necrotic areas, fibrin deposition, and nucleated red blood cell enrichment.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
Medical Imaging Research Center, Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:
Introduction: The persistent sciatic artery (PSA) is a rare congenital vascular anomaly that arises when the embryonic axial artery fails to regress, potentially leading to serious complications such as limb ischemia.
Case Presentation: We report the case of a 47-year-old woman with a history of essential hypertension and recent hormonal treatment for uterine fibroids. She developed acute limb ischemia due to bilateral PSA thrombosis, which was confirmed through comprehensive imaging.
Front Endocrinol (Lausanne)
December 2024
Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Objective: Polycystic ovary syndrome (PCOS) is an important factor contributing to infertility in reproductive-aged women. Hyperandrogenism (HA) plays an important role in the pathogenesis of PCOS. This study was conducted to explore the follicular development and endometrial receptivity of different androgen phenotypes in reproductive-aged patients with PCOS.
View Article and Find Full Text PDFCureus
November 2024
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, IND.
In preeclampsia, there occurs a defective trophoblastic invasion of spiral arteries, which is characterized by abnormal uterine artery wave parameter such as increased pulsatility index (PI) and early diastolic notch. This increased uterine artery PI is a good predictor of hypertensive disorder and small for gestational-age babies. Maternal hypertension and proteinuria resolve in the puerperium.
View Article and Find Full Text PDFArch Gynecol Obstet
December 2024
Maternal and Fetal Medicine Unit, São José Local Health Unit, Centro Clínico Académico de Lisboa, Lisbon, Portugal.
Objective: This study aimed to investigate the association between maternal factors and first-trimester biophysical and biochemical markers with small for gestational age (SGA) neonates in twin pregnancies (TwPs).
Methods: Single-center retrospective cohort study of TwPs followed from January 2010 to December 2022 at a tertiary perinatal center, Portugal. Maternal and pregnancy characteristics, mean arterial pressure, pregnancy-associated plasma protein-A (PAPP-A), β-human chorionic gonadotropin (β-HCG), and uterine artery pulsatility index (UtA-PI) were analyzed.
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