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| http://dx.doi.org/10.1016/j.gendis.2023.101076 | DOI Listing |
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Validation of the Arabic Version of the Maslach Burnout Inventory-HSS Among Tunisian Medical Residents (A-MBI-MR): Factor Structure, Construct Validity, Reliability, and Gender Invariance.
Healthcare (Basel)
January 2025
Higher Institute of Sport, and Physical Education of Sfax, University of Sfax, Sfax 3000, Tunisia.
: Burnout is a major problem for physical and mental health of medical residents. The key for maintaining well-being and quality of care of residents is the assessing tool. The study evaluated the psychometric properties of the Arabic version of the Maslach Burnout Inventory Human Services Survey (MBI-HSS) among Tunisian medical residents by assessing its factor structure, construct validity, reliability, and gender invariance.
View Article and Find Full Text PDFOccupational Burnout in Nurses and Corporate Employees in Małopolska Region, Poland.
Healthcare (Basel)
January 2025
Department of Nursing Management and Epidemiological Nursing, Faculty of Health Sciences, Jagiellonian University Medical College, 31-008 Krakow, Poland.
: Work is an essential aspect of human life. However, high expectations from employers and clients, combined with time pressure and chronic stress, can contribute to burnout among employees in service professions. : This study aimed to compare the prevalence of burnout syndrome between two occupational groups-corporate office workers and active nurses-and to assess the influence of socio-demographic factors on the level of burnout in both groups.
View Article and Find Full Text PDFCD163 impairs HBV clearance in mice by regulating intrahepatic T cell immune response via an IL-10-dependent mechanism.
Antiviral Res
January 2025
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China; State Key Laboratory of Organ Failure Research; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education; Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases; Guangdong Provincial Clinical Research Center for Viral Hepatitis; Guangdong Institute of Hepatology; Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology. Electronic address:
Background & Aims: Chronic hepatitis B (CHB) arises from a persistent hepatitis B virus (HBV) infection, complicating efforts for a functional cure. Kupffer cells (KCs), liver-resident macrophages, are pivotal in mediating immune tolerance to HBV. Although CD163 marks M2-polarized KCs, its precise role in HBV infection remains unclear and warrants further investigation.
View Article and Find Full Text PDFUnlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation.
Gut
January 2025
Division of Clinical Microbiology,Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden
Background: Tumour-infiltrating T cells can mediate both antitumour immunity and promote tumour progression by creating an immunosuppressive environment. This dual role is especially relevant in hepatocellular carcinoma (HCC), characterised by a unique microenvironment and limited success with current immunotherapy.
Objective: We evaluated T cell responses in patients with advanced HCC by analysing tumours, liver flushes and liver-draining lymph nodes, to understand whether reactive T cell populations could be identified despite the immunosuppressive environment.
Burnout in Military Orthopedic Surgeons: A Multicenter, Cross-Sectional Study.
Mil Med
January 2025
Department of Orthopaedics, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.
Background: High rates of burnout are prevalent in U.S. physicians with evidence that the rates are increasing.
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