Background: Halitosis in children implies psychosocial repercussions. Risk factors associated with this condition are unclear, and detection methods are inaccurate.
Aim: To quantify the levels of sulfur-like compounds in children with asthma and healthy children from a novel validated assay, and to establish the risk factors related to halitosis.
Design: One hundred and twenty-eight individuals (63 healthy and 65 asthmatic) from 3 to 17 years of age were tested using a passive colorimetric sensor to measure the levels of sulfur-like compounds in breath and saliva. Information was collected on oral hygiene habits, gingival and dental health, breathing type, and dental malocclusion.
Results: The mean values of hydrogen sulfide were 4.0 ± 6.8 and 19.7 ± 12.2 ppbv (parts per billion in volume) in the control and asthmatic groups, respectively (p < .001). The presence of higher concentrations of sulfur compounds was significantly associated (p < .05) with the presence of gingival inflammation, tongue coating, dental plaque, mouth breathing, hypomineralization, age, tongue brushing, and the use of dental floss.
Conclusion: The level of sulfur in breath and saliva was significantly higher in patients with asthma. These results can serve as a precedent to raise awareness among paediatricians and parents about oral hygiene care in children and adolescents.
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http://dx.doi.org/10.1111/ipd.13178 | DOI Listing |
Proteomics Clin Appl
December 2024
Department of Medical and Clinical Biophysics, Faculty of Medicine, University of P.J. Šafárik in Košice, Košice, Slovakia.
Purpose: During COVID-19, significant changes in protein abundance can be linked with disease-related processes. The mass spectrometry-based proteomics of COVID-19-related biomarkers can help with the prognosis and diagnosis of this severe disease.
Design: Here, we surveyed scientific works in terms of proteomic analysis of solid tissues and non-blood fluids from COVID-19 patients.
Heliyon
December 2024
Division of Pediatric Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Obstructive Sleep Apnea (OSA) is a common sleep-related breathing disorder characterized by airway obstruction during sleep. Diagnosing pediatric OSA is challenging, particularly in underrepresented populations, leading to disparities in treatment and long-term negative health outcomes. Our study aimed to identify alternative diagnostic tools by investigating genome-wide epigenetic changes and associated transcriptomic alterations in Black female, pediatric patients with OSA.
View Article and Find Full Text PDFClin Exp Med
December 2024
Department of Physics, Faculty of Natural Science, Ariel University, 40700, Ariel, Israel.
This review paper explores the realm of non-invasive methods for early cancer detection. Early identification is crucial for effective therapeutic intervention, and non-invasive techniques have emerged as promising tools to enhance diagnostic accuracy and improve patient outcomes. The paper thoroughly examines the advantages, limitations, and prospects of various non-invasive approaches, including blood tests, non-blood-based tests, and diverse imaging modalities.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Facultad de Ciencias Económicas, Universidad Central del Ecuador, Quito 170521, Ecuador.
This paper offers a systematic review of advancements in electronic nose technologies for early cancer detection with a particular focus on the detection and analysis of volatile organic compounds present in biomarkers such as breath, urine, saliva, and blood. Our objective is to comprehensively explore how these biomarkers can serve as early indicators of various cancers, enhancing diagnostic precision and reducing invasiveness. A total of 120 studies published between 2018 and 2023 were examined through systematic mapping and literature review methodologies, employing the PICOS (Population, Intervention, Comparison, Outcome, and Study design) methodology to guide the analysis.
View Article and Find Full Text PDFNature
December 2024
Institute of Translational Medicine, ETH Zurich, Zurich, Switzerland.
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