[Association between unhealthy lifestyles and diabetic dyslipidemia in occupational population and network analysis].

Zhonghua Liu Xing Bing Xue Za Zhi

West China School of Public Health/The Fourth Hospital of West China, Sichuan University, Chengdu 610041, China Affiliated Hospital of Chengdu University, Chengdu 610081, China International Institute of Spatial Lifecourse Health, Wuhan University, Wuhan 430072, China.

Published: March 2024

To understand the influence of unhealthy lifestyle on diabetic dyslipidemia and the key influencing factors in occupational population and provided scientific evidence for the prevention of diabetic dyslipidemia. Based on baseline data and follow-up data of Southwest Occupational Population Cohort from China Railway Chengdu Group Co., Ltd. during 2021. Diabetic dyslipidemia was defined as diabetes plus one or more forms of dyslipidemia, and unhealthy lifestyle factors included smoking, alcohol consumption, unhealthy dietary patterns, low physical activity, and abnormal BMI. Multivariate logistic regression model was used to analyze the relationship between unhealthy lifestyle scores and diabetic dyslipidemia, network analysis was used to find and explore the key lifestyles influencing glycolipid metabolism. A total of 25 631 subjects were included. People with unhealthy lifestyle score 2 and 3 were 1.93 (95%: 1.31-2.86) times and 2.37 (95%: 1.60-3.50) times more likely to have diabetes with ≥1 forms of dyslipidemia than those with scores of 0; People with unhealthy lifestyle score 1, 2 and 3 were 1.98 (95%: 1.08-3.61) times, 2.87 (95%: 1.60-5.14) times and 3.95 (95%: 2.22-7.06) times more likely to have diabetes with ≥2 forms of dyslipidemia than those with score 0. Network analysis found that abnormal BMI and HDL-C were the "bridge nodes" that link unhealthy lifestyles with diabetic dyslipidemia. The higher the score of unhealthy lifestyle, the higher the risk for diabetic dyslipidemia, abnormal BMI and HDL-C are key factors influencing the association between unhealthy lifestyle and diabetic dyslipidemia.

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http://dx.doi.org/10.3760/cma.j.cn112338-20230715-00007DOI Listing

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