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Lidocaine-Based Local Anesthesia Is Essential During Radial Arterial Puncture for Arterial Blood Gas Sampling in a High-Altitude Environment.
High Alt Med Biol
June 2024
Department of Cardiology, The General Hospital of Western Theater Command, Chengdu, People's Republic of China.
Effect of adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia vs general anesthesia only on plasma and cerebrospinal fluid pro-inflammatory cytokine concentrations in patients with cerebral aneurysm: a randomized controlled trial.
Croat Med J
August 2021
Marijana Matas, Department of Anesthesiology, Reanimatology and Intensive Care Medicine, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia,
Aim: To compare the effect of adjunctive lidocaine-based scalp block and laryngotracheal local anesthesia vs general anesthesia only on pro-inflammatory cytokine concentrations in patients with non-ruptured brain aneurysms undergoing elective open surgery.
Methods: This parallel, randomized, controlled, open-label trial was conducted at Clinical Hospital Center Zagreb between March 2019 and March 2020. At the beginning of anesthesia, lidocaine group received 40 mg of 2% lidocaine for laryngotracheal topical anesthesia and 4 mg/kg for the scalp block.
Pharmacokinetics of lidocaine after bilateral ESP block.
Reg Anesth Pain Med
January 2021
UOC Anesthesia and Intensiva Care Unit, Padua University Hospital, Padova, Italy.
Introduction: Erector spinae plane (ESP) block is an emerging interfascial block with a wide range of indications for perioperative analgesia and chronic pain treatment. Recent studies have focused their attention on mechanisms of action of ESP block. However, the pharmacokinetics of drugs injected in ESP is, as of now, uninvestigated.
View Article and Find Full Text PDFRandomized Safety and Feasibility Trial of Ultra-Rapid Cooling Anesthesia for Intravitreal Injections.
Ophthalmol Retina
October 2020
Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan.
Purpose: To test the safety and preliminary efficacy of rapid, nonpharmacologic anesthesia via cooling for intravitreal injections.
Design: Single-center, randomized phase 1 dose-ranging safety study (ClinicalTrials.gov identifier, NCT02872012).
Are teething gels safe or even necessary for our children? A review of the safety, efficacy and use of topical lidocaine teething gels.
J Paediatr Child Health
April 2020
Pharmacy Australia Centre of Excellence, University of Queensland, Brisbane, Queensland, Australia.
Lidocaine-based teething gels have been widely available in Australia for decades in both commercial preparations and those compounded by pharmacies. However, many case reports have highlighted potential risks and toxicity associated with lidocaine-based teething gels when used in infants and young children, including seizures, respiratory arrest and death. The Australian and New Zealand Society of Paediatric Dentistry and the American Academy of Paediatrics do not recommend topical agents for teething, and the US Food and Drug Administration does not recommend topical lidocaine for this purpose due to concerns of toxicity.
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