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http://dx.doi.org/10.3389/fragi.2023.1345486 | DOI Listing |
Front Cardiovasc Med
January 2025
Thrombosis Expertise Center, Maastricht University Medical Centre, Maastricht, Netherlands.
Neurol Sci
January 2025
Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Via Mosè Bianchi 90, 20149, Milan, Italy.
Objective: Plasma glial fibrillary acidic protein (pGFAP) and plasma neurofilament light chain (pNfL) levels reflect astrocyte activation and neuronal damage, respectively. Whether these phenomena play a role in migraine is unknown. This study aimed to compare pGFAP and pNfL levels in patients with chronic migraine (CM) and age-matched controls and to analyze their relation with clinical features.
View Article and Find Full Text PDFEur J Trauma Emerg Surg
January 2025
Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, USA.
Purpose: Our study explores the utilization of objective tools for preoperative assessment of elderly patients by Emergency General Surgeons (EGS).
Methods: A descriptive cross-sectional survey was conducted via the European Society for Trauma and Emergency Surgery (ESTES) Research Committee. EGS were invited through the ESTES members' mailing list and social media platforms.
Front Med (Lausanne)
January 2025
Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Background: Frailty, a geriatric syndrome associated with adverse outcomes, lacks a universal definition. No consensus exists on the most effective frailty scale for predicting mortality.
Methods: This prospective observational study followed community-dwelling volunteers for 6 years.
Objectives: To evaluate the impact of hospitalisation for infectious diseases on the Health-Related Quality of life (HRQOL), multidimensional frailty, and functioning of older patients, we conducted a longitudinal matched cohort study in four European countries.
Methods: HRQOL, frailty, and functioning were assessed using validated questionnaires at inclusion, at discharge, and up to six months later (M6) in patients aged over 65 years hospitalised for severe acute respiratory or bloodstream infections, and matched controls hospitalised for non-infectious conditions. Comparative analyses employed multilevel mixed-effect linear or logistic models to assess changes from inclusion.
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