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DMNAG: Prediction of disease-metabolite associations based on Neighborhood Aggregation Graph Transformer.
Comput Biol Chem
December 2024
School of Computer and Communication, Lanzhou University of Technology, Lanzhou 730050, China. Electronic address:
The metabolic level within an organism typically reflects its health status. Studying the relationship between human diseases and metabolites helps enhance medical professionals' ability for early disease diagnosis and risk prediction. However, traditional biological experimental methods often require substantial resources and manpower, and there is still room for improvement in the performance of existing predictive models.
View Article and Find Full Text PDFDFedGFM: Pursuing global consistency for Decentralized Federated Learning via global flatness and global momentum.
Neural Netw
December 2024
The School of Cyber Science and Technology, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China. Electronic address:
To tackle high communication costs and privacy issues in Centralized Federated Learning (CFL), Decentralized Federated Learning (DFL) is an alternative. However, a significant discrepancy exists between local updates and the expected global update, known as client drift, which arises from inconsistency and heterogeneous data. Previous research in the DFL field has focused on local information during client updates, without considering global information, which fails to alleviate the client drift issue.
View Article and Find Full Text PDFVisualizing Hydrogen Peroxide Diffusion in Soils with Precipitation-Based Fluorescent Probe.
Environ Sci Technol
January 2025
Department of Environmental Science, Zhejiang University, Hangzhou 310058, China.
Hydrogen peroxide (HO)-based advanced oxidation technology has emerged as a cost-effective and green solution for tackling soil pollution. Given the highly heterogeneous nature of soil, the effectiveness of HO remediation is significantly influenced by its diffusion distance in soils. However, the dynamics of HO diffusion and its effective range remain largely unexplored, primarily due to the lack of analytical methods for mapping HO in soils.
View Article and Find Full Text PDFTackling ALT-positive neuroblastoma: is it time to redefine risk classification systems? A systematic review with IPD meta-analysis.
Neoplasia
December 2024
Department of Pathology, Medical School, University of Valencia, 46010 Valencia, Spain; Incliva biomedical health research institute, 46010 Valencia, Spain; CIBER of Cancer (CIBERONC), 28029 Madrid, Spain. Electronic address:
Background: The heterogeneous prognosis in neuroblastoma, shaped by telomere maintenance mechanisms (TMMs), notably the alternative lengthening of telomeres (ALT) pathway, necessitates a refined risk classification for high-risk patients. Current systems often lack precision, hindering tailored treatment approaches. This individual participant data (IPD) meta-analysis of survival among ALT-positive patients aims to improve risk classification systems, enhancing therapeutic strategies and patient outcomes.
View Article and Find Full Text PDFPrevalence of microvascular complications and associated factors among diabetes mellitus patients in Ethiopia: Systematic review and meta-analysis.
Microvasc Res
December 2024
Department of Medical Laboratory Science, College of Health Sciences, Woldia University, P.O. box 400, Woldia, Ethiopia; Research Center for Tuberculosis and Department of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, Prinshof, 0084 Pretoria, South Africa.
Background: Diabetes mellitus (DM) is a metabolic abnormality affecting 537 million people worldwide. Poor glycemic control, longer duration, and poor medication adherence increased the risk of DM complications. Comprehensive evidence on the pooled prevalence of microvascular complications in DM patients in Ethiopia is not available.
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