AI Article Synopsis
- Starch nanoparticles (SNPs) effectively absorb polyphenols from apple pomace, forming bound polyphenols (P-SNPs) that may benefit human health.
- P-SNPs demonstrated strong antioxidant activity, showed non-toxic effects on organs, and increased short-chain fatty acid (SCFA) production in the gut.
- They also improved antioxidant defenses in various tissues while promoting beneficial gut bacteria and suppressing harmful ones, suggesting their potential in enhancing gut health.
Article Abstract
Starch nanoparticles (SNPs) have the capability to adsorb polyphenol components from apple pomace efficiently, forming bound polyphenols (P-SNPs). These bound polyphenols may have potential bioactivities to affect human health positively. Therefore, in-depth in vivo observation of the antioxidant activity and evaluation of its gut microbiota regulatory function are essential. The results revealed that P-SNPs indicated significant scavenging abilities against DPPH, ABTS, and hydroxyl radicals. Furthermore, the nanomaterials exhibited non-toxic properties, devoid of hepatorenal and intestinal damage, while concurrently stimulating the production of short-chain fatty acids (SCFAs) within the gastrointestinal tract. Notably, P-SNPs significantly enhanced antioxidant capacity in serum, liver, and kidney tissues, fostering the proliferation of beneficial bacteria (Lactobacillus, Bacillus, norank_f__Muribaculaceae) while suppressing pathogenic bacterial growth (Helicobacter, Odoribacter). This study proposes a novel research concept for the scientific use of polyphenols in promoting gut health.
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| http://dx.doi.org/10.1016/j.ijbiomac.2024.130979 | DOI Listing |
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