Purpose: To investigate the impact of after-hours surgery on the outcomes of pediatric kidney transplantation (KT).
Methods: Medical records of pediatric KTs performed at a single institution between 2013 and 2021 were retrospectively reviewed. The population was split into three groups according to the incision time and calendar: ordinary day (8.00 AM - 6.30 PM), day-off, and night-time (6.30 PM - 8.00 AM). The following endpoints were compared: ischemia times, length of surgery, complications, delayed graft function (DGF), primary graft non-function (PGNF), and eGFR at three-month follow-up.
Results: Ninety-six non-living donor KTs were performed, median age 11 (IQR 4.3-14) years and median body weight 26 (IQR 13-50) kg. Forty-one (43%) were performed during night-time and 28 (29%) during day-off. Ischemia times were similar (p = 0.769, p = 0.536). Day-off KTs presented an extended length of surgery (p = 0.011). Thirty-two complications were reported in 31 KTs. No difference in the overall rate of complications, DGF, PNGF, and three-month eGFR was found (p = 0.669, p = 0.383, p = 0.949, p = 0.093). Post-operative bleedings were more common in days-off (p = 0.003).
Conclusion: The number of pediatric KTs performed during after-hours was considerable. Even though similar outcomes were reported, more caution should be focused on the KTs performed in days-off to avoid severe complications.
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http://dx.doi.org/10.1007/s00383-024-05666-4 | DOI Listing |
BMC Sports Sci Med Rehabil
December 2024
Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Background: Kinesio tape (KT) has gained popularity in sports and rehabilitation due to its ease of use and potential benefits. However, its effectiveness is not well understood especially in addressing fatigue, a condition that can impair muscle function and increase the musculoskeletal risk of injury. Given KT's potential impact on muscle activity and recovery, this review aims to evaluate the effects of lower limb KT on pain, strength, and balance following fatigue.
View Article and Find Full Text PDFPharmacoecon Open
December 2024
AxTalis B.V., Gentbrugge, Belgium.
Background: Adequate insulin injection technique (IIT) is crucial to optimize the efficacy of diabetes therapy. Widespread non-practice of injection-site rotation and frequent reuse of insulin pen needles (PN) promote high rates of lipohypertrophy (LH) among people living with diabetes (PwD). LH is associated with increased insulin requirement and suboptimal insulin absorption leading to worsened glycemic control and increased risk for hypoglycemia.
View Article and Find Full Text PDFTranspl Int
November 2024
Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Clin Exp Nephrol
November 2024
Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Introduction: Clinical epidemiological data on monoclonal gammopathy of renal significance (MGRS) are lacking. In this retrospective observational study, MGRS was compared with B-cell or plasma cell malignancies (BCM/PCM) with renal involvement to clarify differences in their clinical features.
Methods: Among the 1408 renal biopsies performed at our hospital, 25 MGRS and 18 BCM/PCM patients were identified.
J Thromb Haemost
November 2024
Division of Hematology, The Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, and the University of Cincinnati College of Medicine, Cincinnati, Ohio, USA. Electronic address:
Background: Understanding of the hemostatic and complement alterations associated with cardiopulmonary bypass (CPB) in pediatric patients and the impact of these alterations on outcome is limited.
Objectives: The present study prospectively characterized these alterations and their association with postoperative outcomes in pediatric CPB.
Methods: All patients aged <21 years undergoing CPB at the authors' institution between 2020 and 2021 who weighed >3 kg, were >36 weeks gestational age, and had no known prothrombotic or hemorrhagic disorders were eligible.
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