Nanoparticle-based pazopanib shows promise in OA.

Nat Rev Rheumatol

Nature Reviews Rheumatology, .

Published: May 2024

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http://dx.doi.org/10.1038/s41584-024-01104-wDOI Listing

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Article Synopsis
  • Osteoarthritis (OA) causes pain and damage to the cartilage in joints.
  • Scientists created a special treatment called Nano-PAZII, which is a tiny particle version of an existing cancer drug that helps with OA.
  • In tests with mice, a single injection of Nano-PAZII reduced joint pain and protected cartilage without causing serious side effects.
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