Complete genome sequence of F12-21, a halotolerant bacterium with antibacterial properties isolated from a Big Bone Lick State Park salt spring.

F12-21 is a halotolerant bacterium isolated from a sulfur-enriched salt spring. F12-21 inhibits bacteria of human health interest and bacterial salt spring co-inhabitants. We report the genome of F12-21, with a predicted genome of 3.77 Mbp containing 3,732 protein-coding genes, 80 tRNAs, and 24 rRNAs.