AI Article Synopsis
Article Abstract
Objective: To characterize late preterm antenatal steroids (AS) use and associated neonatal outcomes in a single academic center.
Study Design: Retrospective study of 503 singleton, mother-infant dyads delivered between 34 0/7 and 36 6/7 weeks gestation between January 1, 2016 and December 31, 2020.
Results: Forty-three percent did not receive AS (No AS) prior to delivery. Among AS treated, 50% were sub-optimal dosing. No AS had higher preterm premature rupture of membranes and maternal diabetes. AS group had lower mean gestational age, birthweight, longer time from admission to delivery and longer NICU stay. There was no difference in neonatal hypoglycemia.
Conclusions: Sub-optimal AS dosing in late preterms remains high in our center. AS did not improve neonatal outcomes. Studies are needed to evaluate the impact of AS in diabetics delivering late preterm, to optimize the timing of AS dosing, and evaluate the longer term impact on late preterm infants.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41372-024-01934-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Effect of Being Born Moderate-to-Late Preterm on Lung Function and Respiratory Morbidity at 9 to 10 Years of Age.
Ann Am Thorac Soc
January 2025
Royal Women's Hospital, Newborn Research, Parkville, Victoria, Australia.
The effect of moderate-late preterm (MLP; 32 to 36 completed weeks' gestation) birth on childhood respiratory health is unclear. To assess the effect of being born MLP, compared with being born at term (≥37 completed weeks' gestation), on lung function and respiratory morbidity at 9-10 years of age. Prospective cohort of children born MLP or at term at the Royal Women's Hospital, Victoria, Australia.
View Article and Find Full Text PDFUnderstanding the Difficulties in Diagnosing Neonatal Sepsis: Assessing the Role of Sepsis Biomarkers.
J Crit Care Med (Targu Mures)
October 2024
Department of Obstetrics and Gynecology, "Victor Babes" University of Medicine and Pharmacy, Timișoara, Romania.
Background: Neonatal sepsis is a serious condition with high rates of morbidity and mortality, caused by the rapid growth of microorganisms that trigger a systemic reaction. Symptoms can range from mild to severe presentations. The causative microorganism is usually transmitted from mothers, especially from the urogenital tract, or can originate from the community or hospital.
View Article and Find Full Text PDFIntroduction: Despite the increasing evidence supporting the use of biologics for treating severe asthma, there is a lack of evidence regarding their use in pregnant women. This study aims to evaluate the safety of biologics for pregnant women, utilizing global pharmacovigilance database.
Methods: Reports documented between 1980 and 2023 were extracted from the VigiBase that mentioned pregnancy- or fetus-related reactions with drugs indicated for asthma, including reslizumab, omalizumab, mepolizumab, dupilumab, benralizumab, and other non-biologics.
The effects of early enteral feeding, fortification, and rapid feeding advancement in extremely low birth weight infants.
Early Hum Dev
January 2025
Division of Neonatology, Department of Pediatrics, Saint Elizabeth's Medical Center, Brighton, MA 02135, United States of America.
Background: Preterm infants are at risk for necrotizing enterocolitis (NEC) and sepsis. Optimal strategies of preterm feeding to achieve full enteral feeding early with minimal duration of central lines without increasing the risk of NEC remain uncertain. We aimed to evaluate if new enteral feeding strategies reflecting early initiation, fortification, and more rapid advancement is beneficial without increasing the risk of NEC.
View Article and Find Full Text PDFDaily participation in preterm-born children: An exploratory and comparative study.
Early Hum Dev
January 2025
Department of Pediatrics, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel; Neonatal Intensive Care Unit, Rambam Health Care Campus, Israel. Electronic address:
Background: Preterm birth, particularly with lower gestational age and respiratory complications, can impact neurodevelopmental outcomes and participation in daily activities. Understanding how these children engage in everyday tasks, particularly from the perspective of their parents, is critical for assessing long-term health outcomes and quality of life.
Objectives: This study aims to assess parental perceptions of participation and daily performance in children born preterm, comparing early preterm infants with and without chronic lung disease, late preterms, and term-born children.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!