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Bone fracture ruptures blood vessels and disrupts the bone marrow, the site of new red blood cell production (erythropoiesis). Current dogma holds that bone fracture causes severe hypoxia at the fracture site, due to vascular rupture, and that this hypoxia must be overcome for regeneration. Here, we show that the early fracture site is not hypoxic, but instead exhibits high oxygen tension (> 55 mmHg, or 8%), similar to the red blood cell reservoir, the spleen.
View Article and Find Full Text PDFEffect of Amaranth-Containing Dietary Intervention in Improving Hemoglobin Concentration: A Systematic Review and Meta-Analysis.
Public Health Rev
January 2025
Faculty of Health Sciences, Hawassa University, Hawassa, Ethiopia.
Objective: Amaranth, a nutritious iron source, is known for treating anemia in young children and lactating mothers, but its effectiveness in reducing hemoglobin concentration needs further investigation. Therefore, this study aimed to summarize the effectiveness of amaranth-based food interventions in improving hemoglobin concentration.
Method: A randomized controlled trial and quasi-experimental study conducted since 2000 were searched in databases like PubMed, Scopus, Embase, Cochrane, AJOL, and Web of Science using prespecified keywords.
Systematic review on supplementation, fortification, and food-based interventions for preventing iron deficiency anemia in low- and middle-income countries.
Asia Pac J Clin Nutr
February 2025
Center for Health and Human Nutrition, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Background And Objectives: Prioritizing key preventive and therapeutic interventions is one of the actions to accelerate the reduction of anemia. This study aimed to examine interventions designed to prevent anemia.
Methods And Study Design: A systematic search was conducted in PubMed, Web of Science, Scopus, and Cochrane Library.
Cognitive disengagement syndrome: The same as or different from attention-deficit hyperactivity disorder? An examination based on biochemical parameters.
J Psychiatr Res
January 2025
Department of Child and Adolescent Psychiatry, Sakarya University Faculty of Medicine, Sakarya, Turkey.
Objectives: The aim of this study was to determine whether there are differences in the biochemical blood parameters between individuals with Cognitive Disengagement Syndrome (CDS) and Attention Deficit Hyperactivity Disorder (ADHD), and to investigate the relationship between vitamin levels and these disorders, as well as their impact on symptom severity.
Methods: The study included 35 patients with ADHD, 35 patients with both ADHD and CDS, and 35 healthy control subjects who presented to the child and adolescent psychiatry outpatient clinic between January 2022 and 2023, matched for age and gender. Children aged 7-15 were included in the study.
Managing blood requirement in a rare P-null phenotype patient during the COVID pandemic in a resource-limited setting.
Asian J Transfus Sci
September 2022
Department of Paediatric Neurosurgery and Craniofacial Surgery, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi, Kerala, India.
We report the case of a 5-year-old girl with a rare P-null phenotype who presented for a neurosurgical procedure at our center. The case is unique as this patient was one of the two P-null phenotype cases reported in India and we report how we could successfully arrange a rare blood unit for her. As it was challenging to find a donor for her, autologous blood was collected.
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