Introduction And Significance: Intraductal papilloma (IDP) is a benign breast lesion characterized by a small, delicate wart-like growth found within the milk ducts. Typically located centrally behind the nipple, IDP often presents with a serous, serosanguinous, or bloody discharge from the nipple, making it a common cause of abnormal nipple discharge. Differential diagnosis is crucial as it can be mistaken for other conditions such as pigmented Paget's disease and pigmented basal cell carcinoma.
Case Presentation: This case study depicts a 35-year-old female with a painless, pigmented mass on the nipple of her right breast that had been present for four months. Physical examination revealed a well-defined blue nodule measuring 13 × 8 mm. Although mammography and ultrasound did not detect any abnormalities in the breast tissue, a biopsy confirmed the diagnosis of intraductal papilloma. The lesion was surgically excised under local anesthesia without complications.
Clinical Discussion: In this case, IDP presented as a blue nodule near the nipple. Despite the patient's young age and unique presentation, the diagnosis of intraductal papilloma was made based on the identified risk factors for breast tumors. Differential diagnoses considered included mammary Paget disease, nipple duct adenoma, and erosive adenomatosis of the nipple.
Conclusion: This case report underscores the uncommon occurrence of IDP manifesting on the nipple. A thorough evaluation incorporating medical history, physical examination, imaging studies, and cytological analysis is essential for an accurate diagnosis and to exclude malignancy. Surgical excision was successful in removing the lesion.
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http://dx.doi.org/10.1016/j.ijscr.2024.109483 | DOI Listing |
Sci Rep
January 2025
Department of Breast Surgery, Cheeloo College of Medicine, Qilu Hospital (Qingdao), Shandong University, 758 Hefei Road, Qingdao, 266000, Shandong, China.
With the popularity of breast screening, more and more intraductal papillary lesions (IDPL)were detected by ultrasound or mammography, which is a spectrum of diseases ranging from benign to malignant lesions. Patients with pathological nipple discharge (PND) may indicate IDPL, but it is difficult to clarify their biological characteristics before the operation. As to patients with IDPL without PND, it is even an enormous challenge to differentiate their benign or malignant characteristics.
View Article and Find Full Text PDFMed Mol Morphol
December 2024
Department of Pathology, Kurume University School of Medicine, Kurume, Japan.
We report a case of solid papillary carcinoma (SPC) that developed at the site of a previous intraductal papilloma (IDP) with atypical ductal hyperplasia. This case supports IDP as a potential precursor lesion to SPC.
View Article and Find Full Text PDFJ Clin Exp Dent
November 2024
DDS, PhD. Oral Pathology Unit, Department of Clinic and Preventive Dentistry, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Inverted ductal papilloma is an uncommon benign papillary endophytic tumor. This report aimed to present a case of inverted ductal papilloma of the oral cavity. A 54-year-old female patient presented with an asymptomatic nodular lesion on the lower lip.
View Article and Find Full Text PDFCureus
October 2024
College of Medicine, Qassim University, Buraydah, SAU.
Introduction: A breast lesion is an unusual development in the breast tissue that typically appears as a lump or swelling. It encompasses a wide range of disorders, from benign to malignant, posing significant health challenges globally.
Methods: The study was a retrospective study conducted at King Fahad Specialist Hospital (KFSH), Buraidah, Qassim region in Saudi Arabia between March 10, 2017, and April 2, 2024.
Cureus
September 2024
Breast Surgical Oncology, Ironwood Cancer and Research Centers, Scottsdale, USA.
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