Unusual presentation of intraductal papilloma on the nipple: A case report.

Int J Surg Case Rep

Department of Dermatology and Venereology, Aleppo University Hospital, University of Aleppo, Aleppo, Syrian Arab Republic.

Published: April 2024

Introduction And Significance: Intraductal papilloma (IDP) is a benign breast lesion characterized by a small, delicate wart-like growth found within the milk ducts. Typically located centrally behind the nipple, IDP often presents with a serous, serosanguinous, or bloody discharge from the nipple, making it a common cause of abnormal nipple discharge. Differential diagnosis is crucial as it can be mistaken for other conditions such as pigmented Paget's disease and pigmented basal cell carcinoma.

Case Presentation: This case study depicts a 35-year-old female with a painless, pigmented mass on the nipple of her right breast that had been present for four months. Physical examination revealed a well-defined blue nodule measuring 13 × 8 mm. Although mammography and ultrasound did not detect any abnormalities in the breast tissue, a biopsy confirmed the diagnosis of intraductal papilloma. The lesion was surgically excised under local anesthesia without complications.

Clinical Discussion: In this case, IDP presented as a blue nodule near the nipple. Despite the patient's young age and unique presentation, the diagnosis of intraductal papilloma was made based on the identified risk factors for breast tumors. Differential diagnoses considered included mammary Paget disease, nipple duct adenoma, and erosive adenomatosis of the nipple.

Conclusion: This case report underscores the uncommon occurrence of IDP manifesting on the nipple. A thorough evaluation incorporating medical history, physical examination, imaging studies, and cytological analysis is essential for an accurate diagnosis and to exclude malignancy. Surgical excision was successful in removing the lesion.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10958466PMC
http://dx.doi.org/10.1016/j.ijscr.2024.109483DOI Listing

Publication Analysis

Top Keywords

intraductal papilloma
16
nipple
8
case report
8
physical examination
8
blue nodule
8
diagnosis intraductal
8
unusual presentation
4
intraductal
4
presentation intraductal
4
papilloma
4

Similar Publications

Analysis of the clinicopathological and imaging features in breast intraductal papillary lesions with or without pathological nipple discharge.

Sci Rep

January 2025

Department of Breast Surgery, Cheeloo College of Medicine, Qilu Hospital (Qingdao), Shandong University, 758 Hefei Road, Qingdao, 266000, Shandong, China.

With the popularity of breast screening, more and more intraductal papillary lesions (IDPL)were detected by ultrasound or mammography, which is a spectrum of diseases ranging from benign to malignant lesions. Patients with pathological nipple discharge (PND) may indicate IDPL, but it is difficult to clarify their biological characteristics before the operation. As to patients with IDPL without PND, it is even an enormous challenge to differentiate their benign or malignant characteristics.

View Article and Find Full Text PDF

We report a case of solid papillary carcinoma (SPC) that developed at the site of a previous intraductal papilloma (IDP) with atypical ductal hyperplasia. This case supports IDP as a potential precursor lesion to SPC.

View Article and Find Full Text PDF

Inverted ductal papilloma is an uncommon benign papillary endophytic tumor. This report aimed to present a case of inverted ductal papilloma of the oral cavity. A 54-year-old female patient presented with an asymptomatic nodular lesion on the lower lip.

View Article and Find Full Text PDF

Introduction: A breast lesion is an unusual development in the breast tissue that typically appears as a lump or swelling. It encompasses a wide range of disorders, from benign to malignant, posing significant health challenges globally.

Methods: The study was a retrospective study conducted at King Fahad Specialist Hospital (KFSH), Buraidah, Qassim region in Saudi Arabia between March 10, 2017, and April 2, 2024.

View Article and Find Full Text PDF
Article Synopsis
  • - Papillary carcinoma is a rare type of breast cancer, often presenting with bloody nipple discharge and typically showing positive estrogen, progesterone, and HER2 receptors for targeted treatments; however, a rare variant called triple-negative papillary carcinoma (TNPC) lacks these receptors.
  • - A case is presented involving a 43-year-old woman diagnosed with TNPC after an abnormal mammogram, highlighting the challenges in diagnosing and managing this variant due to its unique characteristics.
  • - Treatment primarily involves surgical excision with clear margins, and while adjuvant chemotherapy may be recommended for high-risk cases, there's limited evidence on the effectiveness of targeted therapies and hormone treatments for TNPC, emphasizing the need for more research on appropriate treatment strategies. *
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!