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Background: Nurses face significant risks of excessive daytime sleepiness (EDS), which adversely affects workplace safety and productivity. Yet, the extent of EDS in this workforce remains inadequately characterized.
Aim: The aims of this systematic review were to assess the pooled prevalence of EDS among nurses.
Evaluating PAX1/JAM3 methylation for triage in HPV 16/18-infected women.
Clin Epigenetics
December 2024
Department of Gynecology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310003, China.
Objective: Referring all women who tested positive for human papillomavirus (HPV) 16/18 to colposcopy may lead to potential over-referral issues. Triage tests based on cytology results face challenges in achieving accurate diagnoses. Our study aims to assess the clinical effectiveness of PAX1/JAM3 methylation (CISCER) test as a triage method for HPV 16/18-positive women.
View Article and Find Full Text PDFPrevalence of malaria and associated factors among pregnant women in East Dembia District Northwest Ethiopia.
BMC Pregnancy Childbirth
December 2024
Department of Biostatistics and Epidemiology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Background: Even though several measures have been taken to eliminate malaria, its burden remains persistently high in Sub-Saharan Africa. More than 125 million pregnant women are at risk of getting malaria per year. There is a scarcity of community based evidence on malaria prevalence among pregnant women and associated factors in Northwest Ethiopia.
View Article and Find Full Text PDFInvestigating the inflammatory mechanism of notoginsenoside R1 in Diabetic nephropathy via ITGB8 based on network pharmacology and experimental validation.
Mol Med
December 2024
Department of Nephrology, First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan Province, China.
Background: Diabetes often causes diabetic nephropathy (DN), a serious long-term complication. It is characterized by chronic proteinuria, hypertension, and kidney function decline, can progress to end-stage renal disease, lowering patients' quality of life and lifespan. Inflammation and apoptosis are key to DN development.
View Article and Find Full Text PDFImpact of dementia and mild cognitive impairment on bone health in older people.
Aging Clin Exp Res
December 2024
MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Mild cognitive impairment, dementia and osteoporosis are common diseases of ageing and, with the increasingly ageing global population, are increasing in prevalence. These conditions are closely associated, with shared risk factors, common underlying biological mechanisms and potential direct causal pathways. In this review, the epidemiological and mechanistic links between mild cognitive impairment, dementia and skeletal health are explored.
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