AI Article Synopsis
- This study introduces a method for effectively removing template molecules from molecularly imprinted polymers using heat-activated persulfate, addressing issues with incomplete template removal seen in current techniques.
- The research utilized a polymer designed for Coenzyme Q extraction to test this new approach, ensuring that the heat treatment accurately eliminated the template without compromising the polymer's performance.
- Results showed that this method is efficient and eco-friendly, providing comparable selectivity for target analytes to traditional methods, marking a significant improvement in trace analysis applications.
Article Abstract
This study proposes a new alternative for template removal from molecularly imprinted polymers by heat activated persulfate. It is known that trace amounts of template molecule remains in the polymer network after extraction by current methodologies leading to bleeding and incomplete removal of template which could compromise final determination of target analytes especially in trace analysis. A previously developed molecularly imprinted polymer specially designed for Coenzyme Q (CoQ) extraction was employed as a model to test this template elimination approach. This polymer is based on methacrylic acid and ethylene glycol dimethylacrylate as monomers and Coenzyme Q as template. This coenzyme has the same quinone group as the CoQ10. Selectivity was analyzed comparing the recovery of CoQ and ubichromenol, a CoQ related substance. Chemical degradation using heat-activated persulfate allows the elimination of the template molecule with a high level of efficiency, being a simple and ecological methodology, yielding a polymer that exhibits comparable selectivity and imprinting effect with respect to traditional extraction methods.
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| http://dx.doi.org/10.1016/j.chroma.2024.464783 | DOI Listing |
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