[Predictive factors of severity and mortality in acute community-acquired pneumonia : results of a monocentric study in Tunisia].

Unlabelled: Community-acquired pneumonia (CAP), a frequent reason for hospitalization in pulmonology, is a major cause of morbidity and mortality in adults.

Methods: It is a retrospective, descriptive and analytical study including patients hospitalized for CAP. We studied the predictors of NIV, ICU transfer and hospital mortality.

Results: we included 50 patients (mean age: 56.3 ± 12.8 years). Predictive factors of NIV were PaCO2 ≥ 45 mmHg [Odds Ratio (OR): 15.45, 95 % Confidence Interval (IC): 1.29-184.7], pH ≤ 7.35 (OR: 6.42;1.72-23.9), Fine ≥ 57.5 (OR: 17.36;4.32-693.9) and CURB-65 ≥ 2 (OR: 13.54;1.73-105.7). Taking antibiotics before hospitalization (OR: 1.92;1.08-3.49), PaO2 ≤ 60 mmHg (OR: 4.15;1.27-13.60), Fine score ≥ 100 (OR: 13.54;1.73-105.7) and CURB-65 ≥ 2 (OR: 7.50;1.44-36.9) were associated with the admission in the ICU. PH ≤ 7.35 (OR: 6.39;1.77-23.2) and Fine score ≥ 100 (OR: 8.86;3.33-25.2) were correlated with mortality.

Conclusion: Arterial pH ≤ 7.35, hypoxemia, hypercapnia, CURB-65 ≥ 2, Fine ≥ 100 and taking antibiotics before hospitalization are predictive factors of a poor prognosis of CAP.