In a recent publication, Ramalho et al. investigated monocyte-derived dendritic cell (MODC) mobilization in response to Plasmodium infection. The authors showed that elevated levels of itaconate in MODCs results in reduced CD8 T cell activation and that the absence of itaconate is associated with enhanced parasite control.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10994723 | PMC |
| http://dx.doi.org/10.1016/j.pt.2024.03.003 | DOI Listing |
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