AI Article Synopsis
- A study in Taiwan examined pregnancy outcomes in women with congenital heart disease (CHD) and their children from 2009-2017, identifying 2990 women with 4227 births, categorized into groups based on CHD severity.
- Results showed that women with CHD face significant risks such as stillbirth and preterm birth, and the severity of their condition impacts the health of their offspring, with higher risks of congenital heart defects in children born to women with severe CHD.
- The study suggests that women with CHD should receive enhanced monitoring of heart function during pregnancy, including thorough assessments of fetal health and potential genetic counseling, particularly for those with severe CHD.
Article Abstract
Background: We evaluated the outcomes of pregnancy in women with congenital heart disease (CHD) and their offspring in Taiwan. We also investigated how different severity levels may influence the outcomes.
Methods: We used data (2009-2017) from the Birth Certificate Application database in Taiwan, which is linked to the National Health Insurance Research Database and Taiwan Maternal and Child Health Database. We identified 2990 women with CHD who had 4227 births. Based on the CHD subtypes, patients were further divided into "severe CHD" and "simple CHD" groups.
Results: Women with CHD have a significant risk of stillbirth. In maternal cardiac events, they had the highest risk of heart failure, followed by arrhythmia. The severity of CHD had a significant effect on the outcomes as well. The neonatal birth event that mothers with CHD have the highest risk of is preterm birth at < 32 weeks of gestation. The prominent difference in neonatal morbidities between mothers with severe and simple CHD is recurrent CHD in the offspring. The offspring of the severe CHD group had a higher risk of severe CHD, whereas those of the simple CHD group had a higher risk of simple CHD.
Conclusion: During pregnancy, the monitoring of heart function and cardiac rhythm could be more intensive in mothers with CHD. In addition to accurately assessing fetal growth and development during antenatal care, mothers with severe CHD should be provided with careful fetal heart structure assessment and genetic testing along with counseling.
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| http://dx.doi.org/10.1016/j.jfma.2023.11.009 | DOI Listing |
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