AI Article Synopsis
- Traditional medicine has used Hibiscus sabdariffa for various treatments, and this study analyzed its extract for producing silver nanoparticles.
- The extract contained notable amounts of phenolics (84.9 mg/gm) and flavonoids (41.50 mg/gm) and exhibited antibacterial properties against E. coli and Staphylococcus aureus with a 75.15% scavenging activity.
- The silver nanoparticles were stable for 30 days, measured 21.22 nm, and showed potential cytotoxicity against lung cancer cells and anti-inflammatory effects, suggesting further research is needed for their medicinal use.
Article Abstract
Traditional medicine has long employed the shrub Hibiscus sabdariffa to treat a variety of illnesses. The biochemical characteristics of silver nanoparticles made using the plant extract of Hibiscus sabdariffa were examined in this work. According to the results, the plant extract of Hibiscus sabdariffa had a total phenolic quantity of 84.9 mg/gm and a total quantity of flavonoids of 41.50 mg/gm. The extract also showed antibacterial action against Escherichia coli and Staphylococcus aureus (75.15% scavenging activity). The silver nanoparticles of plant extracts were stable in PBS solution for at least 30 days and had a mean size of particles of 21.22 nm. Silver nanoparticles were shown to both be cytotoxic on human lung cancer cell line A-549 and have anti-inflammatory action. Overall, the research's findings demonstrate the fascinating biological activity of the silver nanoparticles made from the extract of the Hibiscus sabdariffa plant. To assess these compounds' potential as medicines, more research is required.
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| http://dx.doi.org/10.1007/s12010-024-04901-x | DOI Listing |
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